DreEX0051129 @ danRer10
Exon Skipping
Gene
ENSDARG00000043130 | notch2
Description
notch 2 [Source:ZFIN;Acc:ZDB-GENE-000329-4]
Coordinates
chr8:19577462-19580301:+
Coord C1 exon
chr8:19577462-19577604
Coord A exon
chr8:19579512-19579713
Coord C2 exon
chr8:19580211-19580301
Length
202 bp
Sequences
Splice sites
3' ss Seq
ACTGTCCTCTTCCACCTCAGCCA
3' ss Score
7.24
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
ATCGAGGGTTCACCTGGAGATTGACAATCGGCTGTGTACTCAGAACTCAGACGAATGCATCTCCAGTGCAGACCAGGCTGCAGCCTTTATAGCTGCTGAGTACCTGAAGTCAGATCTGCCGTACCCTATCTACTCCATCACCA
Seq A exon
CCAAGCCACCTAAAGAAACTGGGTTTAATTTCCTGTACCTGGTTGCTGTGGCTGCTGCCATCATCCTGCTCATTTTGGTGCTGGGTGTTTTGGCTGCCAAGCGCAAACGCAAGCACGGCACTCTGTGGCTTCCTGATGGCTTTCTGCCAAACAAAGAGAGCAAGCGGAGGGAGCCAGTGGGACAGGATGACTTTGGCATGAA
Seq C2 exon
GAGCATGCAGAAGCCACAGGATGGAGGATTATTGGATTGCAGTTCGAACCATCACTGGTCAGAAGAAGATCATCTTCCTAAAAAACCTAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000043130-'29-32,'29-30,30-32
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.257 C2=1.000
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(80.0=100)
A:
PF076847=NODP=PD(13.3=11.8)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTTCACCTGGAGATTGACA
R:
AGATGATCTTCTTCTGACCAGTGA
Band lengths:
213-415
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002958; ELM sequence: LWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]