DreEX6000071 @ danRer10
Exon Skipping
Gene
ENSDARG00000100143 | lrp6
Description
low density lipoprotein receptor-related protein 6 [Source:ZFIN;Acc:ZDB-GENE-090821-1]
Coordinates
chr4:169196-172667:-
Coord C1 exon
chr4:172531-172667
Coord A exon
chr4:169786-169883
Coord C2 exon
chr4:169196-169709
Length
98 bp
Sequences
Splice sites
3' ss Seq
ATGTCTCTGCTGTTCTGCAGATC
3' ss Score
10.4
5' ss Seq
CAGGTAACA
5' ss Score
8.88
Exon sequences
Seq C1 exon
GCATGTCCAGAGGGAAGTCAGTCATGGGCTCGCTGAGCATCATGGGAGGCAGCAGTGGACCACCGTACGACCGCGCTCATGTGACCGGAGCCTCGTCCAGCAGCTCGTCCAGCACTAAAGGAGCATATTTCCCTCCG
Seq A exon
ATCCTGAACCCTCCTCCATCTCCAGCCACCGTCAGGTCTCAGTACACCATGGAGTTCGGCTACTCCTCCAACAGCCCGTCAACACACCGCTCCTACAG
Seq C2 exon
CTATCGGCCGTACAGTTACCGCCACTTCGCTCCTCCGACGACGCCGTGCAGCACGGATGTGTGCGACAGTGACTATACGCCGGGCCGCCGGGCTCCGCACGCATCCAGCGCCACTGCTGCTAAAGGCTACGCTAGCGACCTGAACTACGACTCGGAGCCGCTGCCGCCGCCGCCCACGCCGCGCAGCCAGTACCTGTCGGCGGAGGAGAACTGCGAGAGCTGCCCGCCGTCACCGTACACCGAGCGCAGCTACTCGCACCAGCTGTACCCGCCGCCGCCCTCGCCCTGCACAGACTCCTCCTGAGCCCCGCCCCCTGCGCGCCAGGCCCCGCCCCCACTGCCTCTGTACATATATATAAGTGACTGTGTCTCGCTGAAGGACAGCTGAGGGCTCTGGCGGCGCTGTACAGTAAGAGAAGAGCATATTTATATATTTCTATACAGTGTTGCCGCGGTTACCCACACGTGGACACTGATGAAGAGAGATTTATCAGACCCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000100143-'44-43,'44-42,46-43=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.457 A=0.606 C2=0.782
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
ENSDART00000166440fB3639
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTCCAGCACTAAAGGAGCAT
R:
GTCGTAGTTCAGGTCGCTAGC
Band lengths:
183-281
Functional annotations
There are 1 annotated functions for this event
PMID: 14731402
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, mutation analysis, mutation disrupting interaction. ELM ID: ELMI002902; ELM sequence: PPPSPA; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]