RnoEX6015367 @ rn6
Exon Skipping
Gene
ENSRNOG00000006338 | Lrp6
Description
LDL receptor related protein 6 [Source:RGD Symbol;Acc:1304749]
Coordinates
chr4:168194927-168204241:-
Coord C1 exon
chr4:168204131-168204241
Coord A exon
chr4:168198106-168198203
Coord C2 exon
chr4:168194927-168195972
Length
98 bp
Sequences
Splice sites
3' ss Seq
TTTAATTGTTTTCCTTTTAGATT
3' ss Score
10.78
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
TGCTTTGTCTAATTGATCAGTTCCGCTGTGCCAATGGTCAGTGCGTTGGAAAACACAAGAAATGCGACCACAATGTGGACTGCAGTGACAGATCTGATGAACTGGACTGCT
Seq A exon
ATTTTGAACCCACCACCATCGCCTGCCACAGAGCGATCCCATTATACCATGGAGTTTGGCTATTCTTCCAACAGTCCTTCCACACATAGGTCCTACAG
Seq C2 exon
CTACAGGCCGTACAGCTACCGGCACTTTGCACCGCCCACTACACCCTGCAGCACTGATGTCTGTGACAGTGACTATGCTCCTAGCCGGAGAATGACCTCAGTGGCAACAGCCAAGGGCTACACCAGTGACTTGAACTATGACTCAGAACCTGTGCCCCCACCACCCACACCCCGAAGCCAGTACTTGTCGGCAGAGGAGAACTATGAAAGCTGCCCCCCTTCTCCATACACTGAGAGGAGTTACTCCCATCACCTCTACCCACCACCACCTTCCCCCTGCACGGACTCCTCCTGAGGAGGGCCCCTCCTCCTCTGACTGCCTCCACCGGGACATGTAAATACACATCTGGTTGAGATCTGGAGGGGGGGAGGGAGCTACAGAAAAGAGTGAGGCAGACCTGTACAGTTAACATAAAGTGGGTGGGGTACCTGAGATATTTGTACAGAAGAAAAGGATATTTATATATTTTCTTAAAACAGCAGATTTGCTGCTTGTGCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000006338-'28-39,'28-37,33-39=AN
Average complexity
A_C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.623 C2=0.467
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=97.4)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTCAGTGCGTTGGAAAACA
R:
TGAGGTCATTCTCCGGCTAGG
Band lengths:
177-275
Functional annotations
There are 1 annotated functions for this event
PMID: 14731402
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, mutation analysis, mutation disrupting interaction. ELM ID: ELMI002902; ELM sequence: PPPSPA; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]