GgaEX6003135 @ galGal4
Exon Skipping
Gene
ENSGALG00000011558 | LRP6
Description
low density lipoprotein receptor-related protein 6 [Source:HGNC Symbol;Acc:HGNC:6698]
Coordinates
chr1:71833436-71838642:-
Coord C1 exon
chr1:71838506-71838642
Coord A exon
chr1:71836768-71836865
Coord C2 exon
chr1:71833436-71834642
Length
98 bp
Sequences
Splice sites
3' ss Seq
TTTTCTTAATTTTTCCTTAGATT
3' ss Score
9.83
5' ss Seq
CAGGTAATT
5' ss Score
8.55
Exon sequences
Seq C1 exon
GGATGTCTCGAGGAAAATCTGTGATCAGCTCCCTCAGCATTATGGGAGGGAGCAGTGGGCCACCCTATGACAGGGCCCATGTCACTGGAGCATCTTCCAGTAGTTCTTCAAGTACGAAAGGCACTTACTTTCCTCCA
Seq A exon
ATTTTGAACCCACCACCATCACCAGCTACTGAACGTTCACATTATACAATGGAATTCGGTTATTCTTCAAACAGCCCATCCACTCATAGATCTTACAG
Seq C2 exon
CTACAGGCCTTACAGCTACCGCCACTTTGCACCTCCCACAACACCCTGTAGCACGGATGTCTGTGACAGTGACTATGCCCCAAGCCGAAGGGTCACGGCCACAATGGCCAAGGGCTACACCAGTGACTTGAACTATGACTCAGAGCCCGTCCCACCGCCTCCGACCCCACGCAGCCAGTACCTGTCAGCGGAGGAGAACTACGAGAGCTGCCCCCCTTCACCATACACAGAGCGGAGCTACTCTCACCACCTCTACCCACCACCACCGTCCCCCTGCACAGACTCCTCATGAGGGGCAGCCCCCCCTCCATTATCTGCCTCTGCCGTGGAAGTGTAAATACAAAGTGTTCTACCAGGGAGGGGGGAGTTCTTGGCAAGGGGTGAGGTAGAACAGTGTACAGTTAAATGTTATTCAGTTGGGTGGAGGAATACTGGACATATTTGTACAGAAGAAAAAAAGGATATTTATATATTTTTTTAAACAGCAACTGCTGCTTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000011558-'31-47,'31-46,32-47=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.543 A=0.697 C2=0.711
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCATTATGGGAGGGAGCAGT
R:
CACAGACATCCGTGCTACAGG
Band lengths:
167-265
Functional annotations
There are 1 annotated functions for this event
PMID: 14731402
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, mutation analysis, mutation disrupting interaction. ELM ID: ELMI002902; ELM sequence: PPPSPA; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]