MmuEX6007467 @ mm9
Exon Skipping
Gene
ENSMUSG00000030201 | Lrp6
Description
low density lipoprotein receptor-related protein 6 [Source:MGI Symbol;Acc:MGI:1298218]
Coordinates
chr6:134396494-134404851:-
Coord C1 exon
chr6:134404715-134404851
Coord A exon
chr6:134403568-134403665
Coord C2 exon
chr6:134396494-134401098
Length
98 bp
Sequences
Splice sites
3' ss Seq
TTTAATTGTTTTCCTTTTAGATT
3' ss Score
10.78
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GAATGTCTCGAGGCAAATCAATGATCAGTTCCCTCAGTATCATGGGGGGAAGCAGTGGGCCCCCCTATGATCGAGCGCACGTCACGGGAGCCTCCTCAAGCAGTTCTTCCAGTACCAAAGGCACTTACTTCCCTGCA
Seq A exon
ATTTTGAACCCACCACCATCGCCTGCCACAGAAAGATCCCATTATACCATGGAATTTGGTTATTCTTCCAACAGTCCTTCCACACATAGGTCCTACAG
Seq C2 exon
CTATAGGCCGTACAGCTACCGGCACTTTGCACCGCCCACCACACCCTGCAGCACTGATGTCTGTGACAGTGACTATGCTCCTAGCCGGAGGATGACCTCGGTGGCAACAGCCAAGGGCTACACCAGTGACGTGAACTATGACTCAGAACCTGTGCCCCCACCGCCCACACCCCGAAGCCAGTACTTGTCAGCGGAGGAGAACTATGAAAGCTGCCCCCCTTCCCCATACACGGAGAGGAGTTACTCCCACCACCTCTACCCGCCACCACCCTCCCCCTGCACGGACTCCTCCTGAGGAGGGCCCCTCCTCCTCTGACTGCCTCCACCGGGACATGTAAATACACATCTGGTTGAGATCTGGAGGGGGGGAGGGAGCTATAGAGAAGAGTGAGGCAGACTCTGTACAGTTAACATTATAAAGTGGGTGGGTGCTGGAGATATTTGTACAGAAGAAAAGAATATTTATATATTTTCTTAAAACAGCAGTTTTGCTGCTTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030201-'24-27,'24-26,25-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.457 A=0.667 C2=0.724
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTTCCCTCAGTATCATGGGGG
R:
GTCACAGACATCAGTGCTGCA
Band lengths:
178-276
Functional annotations
There are 1 annotated functions for this event
PMID: 14731402
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, mutation analysis, mutation disrupting interaction. ELM ID: ELMI002902; ELM sequence: PPPSPA; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: