DreEX6019670 @ danRer10
Exon Skipping
Gene
ENSDARG00000102260 | TMPRSS6
Description
transmembrane protease, serine 6 [Source:HGNC Symbol;Acc:HGNC:16517]
Coordinates
chr6:216612-217103:-
Coord C1 exon
chr6:217036-217103
Coord A exon
chr6:216768-216946
Coord C2 exon
chr6:216612-216653
Length
179 bp
Sequences
Splice sites
3' ss Seq
GTGTGTGTGTTCTGATACAGTGA
3' ss Score
7.41
5' ss Seq
CCGGTAACA
5' ss Score
5.92
Exon sequences
Seq C1 exon
TTTGAGAAGCTGCTGAGAAACTCTGACCTGTCCAGATTCTTCAACTCCAGCGCCGTCTTCGCCTTCAG
Seq A exon
TGAGGGCAGTGTTGTGGCTCATCTGTGGTTGTGTCTGTCGGTCCCTGTGAGTCTGCATGCAGTGGATCTGCAGCGCATCAACAGCAGTGTGTTCAGAGAGCTGCAGCGCTGCAGTGCAGACCAGCACACCAGCACATATGAGGGACTGGACCTGCTGCTGTCGTCATTCAGCATCACCG
Seq C2 exon
AAACCGACAGCAAAGTTCTAGATCTGTTTCAGGCCACGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000102260-'6-7,'6-6,7-7=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0139015=SEA=FE(20.6=100)
A:
PF0139015=SEA=PD(41.1=72.1)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGAAGCTGCTGAGAAACTCTG
R:
AACGTGGCCTGAAACAGATCT
Band lengths:
106-285
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]