DreEX6024668 @ danRer10
Exon Skipping
Gene
ENSDARG00000016527 | helz2
Description
helicase with zinc finger 2, transcriptional coactivator [Source:ZFIN;Acc:ZDB-GENE-120920-1]
Coordinates
chr6:58595696-58602623:+
Coord C1 exon
chr6:58595696-58596488
Coord A exon
chr6:58596589-58596664
Coord C2 exon
chr6:58599176-58602623
Length
76 bp
Sequences
Splice sites
3' ss Seq
TTCTGCCTTTGATATTTCAGGTG
3' ss Score
9.96
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
TGTTGGAGTGTGAGGCTCTTATGGCACTTAGCTTAGCGGGTAACAATACACGTGTGGTTTTAGCAGGAGATCACATGCAGATGGGACCCAAGCTGTTCTCTGTGAGGCCAGACAAATGTTCTGAGCACACCCTGCTCAATCGCCTCTTCTATCACTACCAAGCCGAAAACAGCGATGTGGCCAAACAAAGCCGGATCATTTTCAATGAAAACTACCGCTCCACAAAAGACATTGTGGATTTTGTATCAACACATTTTTATGTTGGAAGGAGTGATGTGATCAAGGCTAGAGGAAATGTGCCGTCTCATCCCCAACAACATGCTTTGCAGTTTCATCATGTAAGAGGAGAATGCTGTCTGGACCCAATGAGCATGTCCTGGTTCAATGCAGAACAAATTGTAAGAGTCGTTCACATTCTGCAAGAAATAATGAAGGAATGGCCTCAAGAGTGGGGTGCTGCAGATCCAGAATCAGTCTGTGTCCTATCTCAAGGCAGACAG
Seq A exon
GTGTTGGAAATCAGGTATAGACTGCGTTTGCTTGGACTGCCTCGTTTCACTGTAGAGAATGCTGAAAATGTGCAAG
Seq C2 exon
GAAAGCAGTTCAGAGTAATTGTGATTTCCACTGTGCACACCAAGGACAGCCTATTGGAGACGGACAGGACCTGTCTTGAGTTTTTCAATGACATGCGAGTCCTGAACACCATCATGACAAGAGCCCAATCACAAATATTTGTTGTTGGAGATGCCGCTGCACTTTCATGCCATCAGTTCGGTATGTGCTGGAGACTTTGGAGAGCATACATAGAGGAATGCATCAACAAGGAAAGTTGCCACGACCTTACTCTGGATTCTTTAAAGCAAGATCTCCTGGAGATTTCTAAACTCTGCAGGAGCGAGGATGAAGAGAACAGCGATAGTGAATCAACTACATCTGAACTACCGGACACTGAAGACCTAATACTTCAAGAGCTTCTTGATGAGAGCAAAGAAATCAATGTTGCTTTGACAGAGGAAGGATTATTTCCAGTTTTTCAAAATCAGGAAGCATTCAGTAGTGCAAATAACCAAGTTGCAGAAGTATATTATGAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000016527-'8-9,'8-8,9-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.008 A=0.000 C2=0.034
Domain overlap (PFAM):
C1:
PF130861=AAA_11=PD(67.7=49.8),PF130871=AAA_12=PU(61.5=47.5)
A:
PF130871=AAA_12=FE(12.2=100)
C2:
PF130871=AAA_12=PD(25.4=4.5),PF0077314=RNB=WD(100=31.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCCAATGAGCATGTCCTGG
R:
TGGTGTGCACAGTGGAAATCA
Band lengths:
183-259
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]