DreEX6028555 @ danRer10
Exon Skipping
Gene
ENSDARG00000012600 | HELZ2 (2 of 3)
Description
helicase with zinc finger 2, transcriptional coactivator [Source:HGNC Symbol;Acc:HGNC:30021]
Coordinates
chr2:42108227-42114984:-
Coord C1 exon
chr2:42114186-42114984
Coord A exon
chr2:42113395-42113470
Coord C2 exon
chr2:42108227-42112292
Length
76 bp
Sequences
Splice sites
3' ss Seq
CTTTTCTCTTTGATATTTAGGTT
3' ss Score
9.95
5' ss Seq
AAGGTACTT
5' ss Score
8.4
Exon sequences
Seq C1 exon
TGCTGGAAGGTGAAGCTCTAATGGCTCTGGGCTTAGCAGACAAACACACTCGAGTGGTTTTAGCAGGAGACCACATGCAGATGGCTCCAAAACTTTTCTCTGTAACCGATGACAAGAGATCAGAACACACCCTGCTCAATCGCCTCTTCCACTACTATCAGGATCAGAGCATCAACATCGCCAAGAAAAGCAGAATAATCTTTAACGAGAACTACCGCTCGACCACAGAAATTGTGGATTTTGTATCCACTTACTTCTATGTGAGTGATGGGATCAAGGCCAGAGGAGATGTGCATCCACACCCGAGGCTAAAACCCTTGATTTTTCATCATGTCAGAGGAGAATGCCATCTGAGTTCCACCATCACATCCACATCATGGTTAAATTATGCTGAGGTCAACAGTGTGGTAAACATGGTACAAGTGCTTCTGACTGACTGGCCAATGGAATGGGGTGATAAAGACCCAAAGCAGATTTGTGTTCTAAGTGAAGGCCAACAG
Seq A exon
GTTGCTGCCATCAGAATACATCTCCGCAGGAAAGGATTTTATGGAGTGTCGGTTCAGAATTTAGCAAACATTCAAG
Seq C2 exon
GAAAACAGTTCAGGGTCATCATAATAACAACAGTCCACACAAGAGACAAACTTCTTCAGTTAGACTCAAGCTGCCCAGAGTTCTTTGATGATATCCGTGCGCTAAACACCGCCTTGACCAGAGCCCAGTCGCTAGTGGTTGTAATTGGAGATGCTGGTGCTCTTTGTTGCTTTGGAAAGTGTTCAAAAGTCTGGAGGGCCTACATAGAACACTGCATCAGTAAGGGCAGCATTAAACCAGATCATTTCACCAGAGATGTCCTACAGCGAGAAGTGTTGGAAATTTCAAAGTTTCAAAAGACAGAAAATGTTGAAAAGATTGAGACTGTTGTAAACCTCCAGGCTGAAACTGATGCTATATTGAAAGAGATGGAGAACTATGATTCTGATGCACAGAAGTCTGATGATGACAATGAACAAAAGAGGCGGATATTCACTTCCGCTGAAAAAGAAAACCTTTTGGAGATGGTCAGGAATCAGCCTGCTCTCTACAAACGTGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000012600-'5-6,'5-5,6-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.065
Domain overlap (PFAM):
C1:
PF130861=AAA_11=PD(46.6=20.6),PF130861=AAA_11=WD(100=30.7),PF130871=AAA_12=PU(61.5=47.2)
A:
PF130871=AAA_12=FE(12.2=100)
C2:
PF130871=AAA_12=PD(25.4=3.8),PF0077314=RNB=WD(100=23.2),PF0077314=RNB=WD(100=20.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGACTGGCCAATGGAATGGG
R:
CGGTGTTTAGCGCACGGATAT
Band lengths:
179-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]