DreEX6028812 @ danRer10
Exon Skipping
Gene
ENSDARG00000016788 | zeb1a
Description
zinc finger E-box binding homeobox 1a [Source:ZFIN;Acc:ZDB-GENE-070912-124]
Coordinates
chr2:43959679-43972779:-
Coord C1 exon
chr2:43972677-43972779
Coord A exon
chr2:43963878-43965499
Coord C2 exon
chr2:43959679-43960242
Length
1622 bp
Sequences
Splice sites
3' ss Seq
TCATCTTTGTGTTTATCCAGGTG
3' ss Score
10.12
5' ss Seq
AAGGTTGGT
5' ss Score
8.46
Exon sequences
Seq C1 exon
CGGACTGTTACGCAGTCGGGAAGCAGGAAGTTTAAGTGCACAGAATGCTCCAAGGCCTTCAAATACAAGCATCACCTGAAGGAGCACCTGCGCATCCACAGCG
Seq A exon
GTGAGAAGCCATATGAGTGCCCCAATTGTCGAAAACGATTCTCTCACTCGGGATCCTACAGTTCTCACATCAGCAGTAAGAAGTGTTCAAGCATAATCGGCGTCACTCGTACACCTGGAGTGAAAACGACTATAACTATTCCCCGCCCAACTCACATCCTTCTGAGAGAGAAGGTGGTGAACATTACCAACAAGCCTCCGCAAAAGCAGCTCACCCTCAAACAGATCAAACAGGAGCCAGTCGAACACCAACCCAAACCTGCCTCAGCCACTCCTGCCATGGCTGCCACCACAACCAATGGAGTCGTGGCTCCGCAGAGCGTCCTCCAAACATTAGTCCTGCCTACAGTCGGGCTGGTCCAGCCAATCAGCATCAACCTTAGTGACTTACAGAACGCGCTGAATGTGGCAATGGATAGCAATGTCATGAGGCAAATGGTCACTAGCACCAATGCTAACGGAACAAGTGCTAAAATCGTAGGACAAGTTCCAGCGCAGACTCAAGCTGTTGTGTTGCAACCACAGCAGACGCAGTCACAGACGCAGCCGCAGGTGATCTCCGCTATCTCTTTGCCAGTTGTGGGACAAGACGGAAACCCCAAAATAATCATCAACTACAATCCACAGTTAGACCGACAACTCAAGGCTGTAAAAGTAAACACAACGCAGCCCGCTGTGGGGCAAACTAACGTGACGCAGACGAATTCCACAACGTCTAATGTCCCACAGCCGAAAGTGTTGCAGGTTCATTCGCTTCAGTCCAGCTCGTCTGAAAACCAAGCATCAGGAACTGCTAAACCCACACAGGTAAACATCATCAAACCAGTCCAAATGGGAAACCTCAGCAAAACGCCGTCTATAATCAAGATAACCCCTGCCCAGGCCGCCAGGTTGGCGCAAGCTCGGGCGGCACAACCAAAGCTCACCCATCAAACGTTACTGCTGGTGAGGAGGGCAGACGGGTCACAGAGCCTCGTGGTCCGCCAGATGCCAGTCACCAATTCCAACACGCAGGCCACAGAGTTAAAGTCAACCCCGGAAAAGACTACAGACACAGCAACTGAGGAGACGAAGGAGACTGACAATACTGAAAATTGTGAAGAGCAAAACTTGACTGCCCCCATAGGAATCCAAATCAAAACCGAACCAGAATCCCCATCCAAAATTGAACCAGAAATACAGAGTGAAGGAGAGGGGGAGATGCAGGCAGATGAAAATGAAGAGGAAGAAACAGAAACGGCATCAAAAACGGATAAAGTCTCGTGCTCTGGAACAGTTCACGCCGGCGTCTCGTGTGGAGATAACTTTCATAACTATGCGTACTGTCTGCTTTGCGACAGCTGTCCGGGTAAACGTAAAATGCTAGAGAGTAAAGAGAGTAATGCCAAAGCGTCGCCTACCACCATCTCACTCAACTCTCTCCTGGATAAGGATAAGAGTGGCGCAGCAGAACGACTCCTTCCTCTTCTGAAGGCCTACAGTCAGAACCCGGAGCCCACAGAGGAGCAGCTGGCTCAGGTCGCCAAGACAGTCAAACTCCCCCTGGCGGCGGTCACCAAGTGGTACGAGAAGATGCGCTCCAAAAGGATACTGCTGCAGGCTACTGGCAACTCGAAAAACAAG
Seq C2 exon
AAAACACCACCATCTCCTGAGTCTCAAGAACCAACCTCAACTCAAGACACCCGCACTCCCAGTCCCACTCCTCCCCCTGACTCCAGCCCCTCAGAGGAGGAGCAGAACAGAAGCACTGCCTCCCCCGCGTCTCCACCAGCCAGTGTCTCCACTGATGATCTGGTCATTGTGAAGACAGAAGAAGTGGAAGAGGAGCTGCAGTGTGAACCGCTGGACCTCTCGCTTCCCAAATCCAGCTCCACTCTACCCGGAACCATCACTAAGCTACCTGTATCGTCCCAAAAGGAGCCACTCAACCTGAGCAGCCTCAATAAGCAAACTCTGGCAGGCAACACCATCTATGTGGCACAGGGCAGTACGGGGCCATTAAACATTATGTCCGCCTCATTGCCAACGCTGGTGGCCATAGCAGAGCCAGGCGGCGTTCCATGCATCAGCTCTGCAATATCCGGAAACAAGCGCACAATACTCATACCGCAGCTCACCTACACCTACAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000016788-'8-13,'8-11,13-13=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.221 A=0.647 C2=0.617
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PU(38.5=28.6)
A:
PF134651=zf-H2C2_2=PD(57.7=2.8),PF0004624=Homeobox=WD(100=8.9)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGTCGGGAAGCAGGAAGTTT
R:
ATGGTTCCGGGTAGAGTGGAG
Band lengths:
348-1970
Functional annotations
There are 1 annotated functions for this event
PMID: 10567582
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI000085; ELM sequence: PLDLS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]