DreEX6031407 @ danRer10
Exon Skipping
Gene
ENSDARG00000055559 | chrna6
Description
cholinergic receptor, nicotinic, alpha 6 [Source:ZFIN;Acc:ZDB-GENE-090312-91]
Coordinates
chr1:21793826-21800761:-
Coord C1 exon
chr1:21800652-21800761
Coord A exon
chr1:21799417-21800476
Coord C2 exon
chr1:21793826-21794191
Length
1060 bp
Sequences
Splice sites
3' ss Seq
TACTTTTTTTTCTGACACAGTGC
3' ss Score
7
5' ss Seq
GAGGTAAAG
5' ss Score
8.27
Exon sequences
Seq C1 exon
ATATGGAATGACTACAAGCTGAAGTGGTCACCAGCAGAGTTTGATGGAATTGAGTTCATCAGAGTCCCATCCAATAAAATCTGGAGGCCTGACATTGTACTTTACAACAA
Seq A exon
TGCTGTTGGGGACTTCCTGGTGGAGGACAAAACCAAAGCCCTTTTGAAATTTGATGGAACCATCACTTGGGTCCCACCTGCAATTTTCAAATCTTCCTGCCCTATGGACATCACTTACTTTCCTTTTGACTATCAGAACTGCTCTATGAAGTTTGGTTCCTGGACGTATGATAAGGCCAAAATTGACCTGGTTCTTATCGGCTCTAAGGTCAACCTTAAAGACTTCTGGGAAAGTGGAGAGTGGGAGATCATTGATGCACCGGGTTATAAGCATGACATCAAGTACAACTGCTGTGAAGAGATCTACCCAGATATAACCTACAGTTTTTATATACGCCGACTACCCCTCTTCTACACTATCAACCTTATAATCCCCTGCCTCCTCATCTCTTTTCTGACAGTACTGGTTTTCTACCTTCCGTCAGACTGTGGCGAGAAGGTGACCTTGTGCATCTCTGTACTTCTATCTCTCACTGTGTTCCTTCTTGTCATTACGGAAACCATCCCATCTACTTCACTTGTGATCCCTCTGATTGGCGAGTACCTTCTCTTCACCATGATCTTCGTAACCCTCTCTATTGTTATCACTGTCTTTGTACTGAATGTGCACTATCGCACCCCTATGACCCACACTATGCCCAGCTGGGTCCGCACTGTCTTTCTTCGAGCTTTACCCCGCATCATGCTCATGCGCAGGCCTCTTGATCTATCAGAGTCCTCTGGAAAAGGAGGACTAGAAACTGGGGGCTCGTCCGGGACAGGAGCAGGGCGCGGAGGAGAGGGGAAGAAGAGAAAGAATAGTGGATCCCAACAGGGTGCAATGAACTCTCTGGAATTTGGAGAGGGGAAAGCAGCATTGGAAGGAAAGAAAGGAGGATGCCCATGTCATCCACTGAAAGAAGCAACTGAGGGAGATTGTGGGAAAGTCAGCCGTCAATTAAGTCCACAGGCTATTAATACAGTTGTGGCTTTCTCTGTCGTGTCACCGGAGATCAAACAGGCTATTGAAAGTGTGAAGTACATTGCTGAGAACATGAGGAGCCGCAACAAAGCTAAAGAG
Seq C2 exon
GTGGAGGATGATTGGAAGTATGTTGCCATGGTGATTGACCGCATCTTCCTCTGGGTCTTTGTGCTGGTGTGTGTGTTAGGAACTTTGGGCCTCTTCCTGCAACCTTTGATTGGCTTCCTCTCGTAATTAACTATGAAACACTAACCAACAATTTTCTGAGTCACTGACATGCTCCGTATTTATTAATGTCACATGTTCCGTCACTACATCAAGACTCTGATAATATAAACTATACACAGGTGCCCTTGTACAGCAAATATCCAATCAGTTTTCCTCTGCCACTAATCACTTGGATGGTTAAAGGCTGATTTTGGCCTTTTAACAATCATTGACTTTGAAACTTGACTATAAGTGAACCTTCCAATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000055559-'4-6,'4-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.110 C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(17.4=100)
A:
PF0293118=Neur_chan_LBD=PD(55.6=32.5),PF0293211=Neur_chan_memb=PU(87.5=65.3)
C2:
PF0293211=Neur_chan_memb=PD(11.7=73.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAGTGGTCACCAGCAGAGT
R:
TGGATATTTGCTGTACAAGGGCA
Band lengths:
354-1414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]