DreEX6038544 @ danRer10
Exon Skipping
Gene
ENSDARG00000102506 | lrp2a
Description
low density lipoprotein receptor-related protein 2a [Source:ZFIN;Acc:ZDB-GENE-050119-2]
Coordinates
chr9:48885872-48891558:+
Coord C1 exon
chr9:48885872-48886030
Coord A exon
chr9:48889220-48889509
Coord C2 exon
chr9:48891334-48891558
Length
290 bp
Sequences
Splice sites
3' ss Seq
AATGTATTCTGTTTTTGCAGACA
3' ss Score
8.56
5' ss Seq
CAGGTAGAT
5' ss Score
7.25
Exon sequences
Seq C1 exon
GTATATGTACTGGACAGACTGGGGAACCAGTGCAAAGATAGAGCGCGCAACTCTCGGAGGAAACTTCAGGACAGAGATTGTCAACACCAGTCTAGTTTGGCCAAATGGTTTGACGCTGGACTATGATGATCAGAGGCTCTACTGGGCAGATGCCAGCTT
Seq A exon
ACAGAAGATTGAGAGGTGCTCGCTCACCGGCACTAACCGTGAGGTCATTGTAAGCACCGCCATTTACCCATTTGCAATGACAGTTTATGATCAGCATATCTACTGGACGGACTGGAACACGCGCAGCATCTACCGCGCAAACAAGCACGACGGGTCTGATCAGAGGGTGATGCTACAAAATCTTCCATCTCGACCCATGGACATCCACGTCTTATCTAACAGCAAACAGCAGCAGTGCAGCAGTCCCTGCGAACAGTTCAACGGTGGATGCAGCCACATTTGCACTCCAG
Seq C2 exon
GTCCTCAGGGAGCAGAGTGTCAGTGTCCTTCAGAGGGCCGCTGGTATCTGGCCGACAACAAACACTGTATTCCTGACAATGGCACGCGCTGCCAGCCCGGGCAGTTTACTTGCATGAATGGCCGCTGTATCCGCTCACAGTGGAAATGCGACAATGATGATGACTGTGGAGATGGCAGTGATGAACTGGAAAGGGTCTGCGGTAAGACGTGTTGCTTACAGTACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000102506-'42-50,'42-49,43-50=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.051 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=77.8),PF0005812=Ldl_recept_b=PU(23.1=16.7)
A:
PF0005812=Ldl_recept_b=PD(74.4=29.6),PF0005812=Ldl_recept_b=WD(100=40.8),PF146701=FXa_inhibition=PU(37.8=14.3)
C2:
PF146701=FXa_inhibition=PD(59.5=28.9),PF0005713=Ldl_recept_a=WD(100=56.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCAACTCTCGGAGGAAACTT
R:
TCACTGCCATCTCCACAGTCA
Band lengths:
295-585
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]