MmuEX6101919 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69480016-69482383:-
Coord C1 exon
chr2:69482225-69482383
Coord A exon
chr2:69481125-69481414
Coord C2 exon
chr2:69480016-69480219
Length
290 bp
Sequences
Splice sites
3' ss Seq
TTTCTTTCTCTTTGCTTCAGGCA
3' ss Score
10.71
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
GTACATGTATTGGACTGACTGGGGTACCAATGCCAAAATTGAAAGAGCCACACTGGGAGGGAACTTCCGGGTCCCCATTGTGAACACCAGCCTGGTTTGGCCCAATGGACTCACTCTGGACCTGGAGACCGACCTTCTCTACTGGGCGGATGCTAGCCT
Seq A exon
GCAGAAAATAGAGCGCAGTACTCTCACGGGCTCCAACCGAGAAGTTGTCATCAGCACTGCCTTCCATTCCTTTGGCTTAACTGTCTACGGCCAGTACATTTACTGGACAGACTTTTACACCAAAAAAATCTACCGTGCTAACAAGTACGATGGGTCAGACCTGATTGCAATGACCACTCGTTTGCCCACCCAGCCTAGTGGCATCTCCACAGTTGTCAAGACCCAGCAGCAGCAGTGTAGCAATCCTTGTGACCAGTTCAATGGAGGATGCAGCCATATCTGTGCTCCAG
Seq C2 exon
GTCCAAACGGAGCTGAGTGCCAGTGTCCACACGAAGGCAGCTGGTATCTGGCCAACGATAACAAGTACTGTGTGGTGGACACAGGTGCCCGCTGTAATCAGTTCCAGTTCACCTGCCTTAATGGGCGTTGTATCTCTCAGGATTGGAAATGTGACAATGACAACGACTGTGGTGATGGCAGTGATGAGCTGCCCACAGTCTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'50-48,'50-46,51-48=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.010 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=77.8),PF0005812=Ldl_recept_b=PU(23.1=16.7)
A:
PF0005812=Ldl_recept_b=PD(74.4=29.6),PF146701=FXa_inhibition=PU(36.8=14.3)
C2:
PF146701=FXa_inhibition=PD(60.5=33.3),PF0005713=Ldl_recept_a=WD(100=56.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGAAAGAGCCACACTGGGAG
R:
CATCACTGCCATCACCACAGT
Band lengths:
307-597
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types