DreEX6040901 @ danRer10
Exon Skipping
Gene
ENSDARG00000060862 | atxn1b
Description
ataxin 1b [Source:ZFIN;Acc:ZDB-GENE-061218-2]
Coordinates
chr16:25640277-25653480:-
Coord C1 exon
chr16:25652891-25653480
Coord A exon
chr16:25646386-25648476
Coord C2 exon
chr16:25640277-25646292
Length
2091 bp
Sequences
Splice sites
3' ss Seq
TTTCTGTTTGTCTAATGAAGGTA
3' ss Score
7.93
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GTCCCTCCCTCTCTCCGTGTGTGCGTAGTCTGGGCGCCCTGCCAAGTGGAGTGTGTTTTTTGAATGAATACCTGATGAGGCTGCTGAGGCTGACTGGGGGAGGAGGAGCCGTGTTCTCTAGTGCACTGTGTGTGTGTGTGTGTGTGTATGCATGTGTGAAGCGAGAGAGGGAGAGAGAGAGAGAGAGAGAGAGCTGGCAGTCTGTTTGCCTTGCATAACATACGCTGTAGCTCTCACACGTAGGGCTAGTGAAACAGCGCAGACGAGGGGACTTCCTTTACCCTCGGCCCTCCGAGCAATTGTCGAAGGAAGTGGAGGAGAGTGAAGGCAAGGGGGGGAATGTTGGACATGGAAGAAAACGTAAATCAGAGGACTGCATGTGTGACCTGATAGCAGAGCTAAACCTGGACAAAGGACAGCTTGTCAGTGGGTAGAGTGAGTTACACTCGTAGTGCAGAGAGAAAAAGAGAGAGTTCTTAAAGGCTTCCCTATAAAGAAAG
Seq A exon
GTACAGACCAATAGCTATCAGAGAGAGATGATTCCACATGAAGCACATGGATCCTTTCCTGACAGGAGTCCTTCCAATGGGCAAGACTATGGTACAAGTGGAGCAGAGTAATAGGACAATGAAAATCTGAGTTCTGCTTTGCATGTAAAACATTTTGAAAAAGACGAGTGGTTAAATTACAGGAAAAGCTCCAAGACCATGAAGTCTAACCAGGAGCGCTGTAATGAGTGCCTTCCGCCAAAGAAGCGGGAGATTTTAGCACTGGAAGAGAAGCAGGTGCTGGTGTCAGCTGCTGTTAGTGAGAGCCAGAGTGGAGAAAATTTGGCTTGGCTAGCCAGTGTTGCTACCATGGCTAGCATGGCCCACATCCCCAACAATGCAGGCCCATCACATAGCAACAGTTCTGAGCCTGACAGCCCCCCACCATCAAATAAGGCTCTCACTGTGGTGGCAGAGTACCCTCCAACTACTACATCTGCTGGCTTTTCATTCTCTTCCAATAGTTCCACCTACAGAGGAGTCTTGTCGGGGCCTACCGTACTAACAGCAAGTCCTGCGGTTCTCTCCACAAGCCTTCCTCAAACCATAGGTTCCGTCCAATACACACAACTTCCCCCCAATCTCCAGCTCATAGGGCCCTATACAAGTTATATCTCTTCACATATTGTCCCATCCACATCCAGTCCAACACAACCACAGAGAACACCACAAGAGATCTTGGCCACAACAGCTGTCATCTCTCAAGCATCCAGCCTTGATTCACAGAGTCATGTGATTTCTTCTATACCAAATGTTTCCCACAGTCAATGCATCCAGGTCGAGAGTGCTCCTTTGGGTTTGACAGTTTCTTCTCCTTCTACACAACTGCCCCTTCAAATCCATCCACACTCAGCTGTCCTTGCTCCTCATGCCCTGGCTCTCACCCCCTCTCAAGTGGTACTACACTACACCGATGGCTTCATTGCAAAGCAGCCAGACTCCCATCGCAGAGAGGTGCTGAATGGTGCACTAGGGGATGTTACAGTAGTCAAGCACAATACTACAATGGCCAAAGGGATCTCTAGCCAGCCAGATGTTGAACAGAACCACAAGCAAAACCATAACCTGGGTATCCAGACGCAAGCTCAGGTTCTGCTGCCTGCAGACTACACCACTAATGACAGAGCAGGTCTGCAGACTTCGCTGATGCTGGTATCCAGTAGCCACCTTGCAGCAAACAGCAACTCGGACATCCAAAGTATCTTGGGTAAAGACCACTCATCTTTGCACCTTGCTGAGAGAGGAGGGATCTGCCTAGGCAAGCCAATGTCCAGAGTGTCCTCCCTTACTTCTTCAGACAGCCAAGTTTCTCCTGCCTCAACAATTTCCCCCCACACACTCATCCAGGCTCCTCACAATGCTCCTCAACAGGAACTCTCCACCAGCCTTTACTCTGCTACACAGCTCCCAATTATTGGCTACATCACCAGTGCTTCTGGTGGACCTCAGCAAGCAGTAACTGGTTATCAGAGCAACCTGCCACAGCATGTGGTAATCTCAGGCAACCCCTCCTTGCTCATTCCGGTGAGTGCCACTAACATCAATCCGTCTACTGCTGAGCCGGAGGTCACACGCTGTTCTGTCATCCCCAGTTTAGCTAATGCATCAACAGCTCTGCCCCAGACCTTTATTAATACATCCCCACCTGCAGCAGTAGCTTCAGTTCTACCCAATGGTAAAGACATCACAGGGTCTGATGGAGGTCTTGTCCCCTGTGCTGTGCCAAGTCCTACCCAAATACAGCTGCCTGTTCTTTCAGGCAGTGTAGTGAGATCTCCAGTCCCAGCTACACCTCCAATTTCCACAAGCCCTCACAGCTCACCATCATCACCAACAGCAGGACTTCCTCCATTCTTCATGAAGGGCTCTATTATCCAGTTGGCAGATGGCGAATTGAAGCGTGTGGAGGATCTGCGGACAGAGGACTTTGTGCAAAGTGCTGAGGTTAGTGGAGAACTGAAGATTGACTCCAGCACTGTAGAGCGCATAGAGGGCAGCGGCACTCCTAATGCTGTCATCATACAGTTCTCAGTGGGAGAGAACAAAGCCCAG
Seq C2 exon
GTGTGTGTTGAGGTTCTGGTGGAATACCCTTTCTTTGTGTTTGGTCAAGGTTGGTCATCCTGCTGCCCTGATCGCACCACCCAGTTACTAGCGCTATCCTGTGCCAAACTCTCTGTGGGCGATGTCTGTATCTCTCTCACTCTTAAAAGTCTAAAAAATAGCATTCAAAAGAAGGATCATTTTTCAGACTCTGTGATGAAACACAGCCTTTTAAATGCAACCAAAAACAATGGGCCTCTTATGGAAAGACCAACCCAAGTGGATGATCTCAAGAAAGGACACAAAATTCCATCAGAAGTGGAAAATAGTATTGTAGAAAAACTTATTGAGACTTCCAACACAAAAATTGTGTTGTCCCTTTCTGAGAATGGGGGCTCAAATCCTCAGACACTAGTTAATCTTCAGAACCAAGCTGAAAAAACATATACATCCACTGCAGAGAGACCCATTAGTCGCAAGAGGAGATGGTCTGCCCCAGAGAAAGCAGACATGCAGAAGTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000060862-'0-2,'0-1,3-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.353 C2=0.418
Domain overlap (PFAM):
C1:
NA
A:
PF125473=ATXN-1_C=WD(100=6.7),PF085177=AXH=PU(56.5=10.3)
C2:
PF085177=AXH=PD(41.7=24.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 21475249
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI002971; ELM sequence: AWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]