MmuEX6058152 @ mm10
Exon Skipping
Gene
ENSMUSG00000046876 | Atxn1
Description
ataxin 1 [Source:MGI Symbol;Acc:MGI:104783]
Coordinates
chr13:45549758-45697945:-
Coord C1 exon
chr13:45697821-45697945
Coord A exon
chr13:45566573-45568580
Coord C2 exon
chr13:45549758-45557585
Length
2008 bp
Sequences
Splice sites
3' ss Seq
CTCCTCCTCCTCCTCCTCAGAAT
3' ss Score
9.62
5' ss Seq
CAGGTAACC
5' ss Score
8.66
Exon sequences
Seq C1 exon
GTATTTCTAACCTCTCTGCGAAAGAAAGAAAGACACCACCAGAACCTGGGCATCCCAGCTGCTGAGGGAAGTTTCCATGGTGAAGTCTCAGGGAGGCTTCCTGGGAGCAGAGCATAGTGAATGCT
Seq A exon
AATCCGGAGCTGCCACTGCCAGCCTAAAGAACCCACGGGGAGATGATTCCCCATGAAGGGCCTGGATCCCCTACAGAAATCCAATGTGACTCTCTGTTTATCAGACTAAAACCAGAGCCGGCCAGCCAGTGAAACAGCCACCGTGGAGGGGGGACGGCGAAAAATGAAATCCAACCAAGAGCGGAGCAACGAATGCCTGCCTCCCAAGAAACGTGAGATCCCCGCCACCAGCCGGCCCTCGGAGGAGAAGGCCACTGCTCTGCCCAGCGACAACCACTGCGTGGAGGGTGTGGCCTGGCTCCCCAGCACCCCTGGCATCCGCGGCCATGGGGGTGGGCGGCACGGGTCAGCAGGGACTTCCGGGGAGCATGGTTTACAAGGAATGGGTTTACATAAAGCACTGTCCGCAGGGCTGGATTACTCCCCACCCAGTGCCCCCAGGTCAGTCCCCACAGCCAACACGCTGCCCACCGTGTACCCTCCTCCTCAGTCAGGGACCCCGGTGTCTCCTGTGCAGTACGCCCACCTTTCGCATACCTTCCAGTTCATTGGGTCCTCCCAATACAGTGGGCCTTACGCGGGCTTTATCCCTTCCCAGCTGATCTCCCCATCAGGCAACCCGGTCACCAGTGCAGTAGCCTCAGCTGCAGGGGCCACCACTCCATCACAGCGCTCCCAGCTGGAGGCTTATTCCACCCTGCTGGCCAACATGGGCAGTCTGAGCCAGGCACCAGGACATAAGGTTGAGCCCCCTCCGCAGCAGCACCTCAGCAGGGCTGCAGGATTAGTCAACCCGGGGTCCCCTCCTCCACCCACCCAGCAGAACCAGTACATCCATATTTCCAGCTCTCCACAGAGCTCCGGGCGGGCGACATCTCCCCCACCCATCCCGGTCCACCTCCATCCCCATCAGACGATGATCCCGCACACACTCACCCTGGGGCCTTCATCCCAGGTGGTTGTGCAATATAGTGATGCCGGAGGCCACTTTGTTCCTCGAGAGTCCACCAAAAAAGCCGAGAGCAGCAGGTTGCAGCAGGCTATGCAAGCCAAGGAAGTCCTGAATGGGGAGATGGAGAAAAGCCGGAGGTATGGGGCATCATCTTCTGTGGAGCTGAGCCTAGGCAAGGCAAGCAGTAAGTCAGTGCCTCATCCCTATGAGTCCAGGCATGTGGTGGTCCACCCAAGCCCAGCAGACTACAGCAGTCGTGATACCTCCGGGGTCCGTGGATCTGTGATGGTTCTGCCTAATAGCAGCACACCCTCAGCCGACCTGGAGGCCCAGCAGACCACGCATCGAGAGGCCTCCCCATCCACCCTCAATGACAAGAGCGGCCTGCACCTAGGGAAGCCGGGCCACAGGTCTTATGCGCTGTCCCCCCACACGGTCATTCAGACCACACACAGTGCATCAGAGCCTCTCCCGGTGGGCCTACCAGCCACGGCCTTCTACGCTGGCACTCAACCTCCTGTCATCGGCTACCTGAGCGGCCAGCAGCAAGCAATCACCTATGCTGGTGGTCTGCCGCAGCACCTGGTGATCCCAGGTAACCAGCCCCTGCTCATCCCGGTGGGCAGCCCTGACATGGACACGCCTGGGGCAGCCTCGGCCATCGTGACGTCATCACCCCAGTTTGCTGCAGTACCTCACACGTTTGTCACCACCGCCCTGCCCAAGAGCGAGAACTTCAACCCAGAGGCTCTGGTCACCCAGGCTGCCTACCCAGCCATGGTGCAGGCCCAGATCCACCTGCCGGTGGTGCAGTCCGTGGCGTCCCCCACCACGGCGTCTCCCACGCTGCCGCCATATTTCATGAAAGGCTCCATCATCCAGCTGGCCAACGGGGAGCTGAAGAAGGTGGAGGACCTGAAGACGGAGGATTTCATCCAGAGTGCAGAGATTAGCAATGACCTCAAGATCGACTCCAGTACTGTGGAGAGAATCGAGGAGAGCCACAGCCCCGGGGTGGCCGTGATACAGTTTGCTGTTGGTGAACACCGAGCCCAG
Seq C2 exon
GTCAGTGTCGAAGTCTTGGTAGAGTATCCTTTTTTTGTATTTGGACAGGGCTGGTCATCCTGCTGTCCTGAGCGGACCAGCCAGCTCTTTGATCTGCCGTGTTCCAAACTCTCTGTTGGGGACGTCTGCATCTCGCTCACCCTCAAGAACCTGAAGAATGGCTCTGTTAAAAAGGGCCAGCCTGTGGACCCTGCCAGCGTCCTGCTGAAGCAGGCAAAGACCGACAGCCTGGCTGGCAGCAGACACAGATACGCGGAGCAGGAAAACGGAATCAACCAGGGAAGCGCCCAGGTGCTCTCTGAGAATGGCGAACTGAAGTTTCCAGAAAAAATAGGATTGCCTGCAGCACCCTTCCTCAGCAAAATAGAACCGAGCAAACCCACAGCCACGAGGAAGAGGAGGTGGTCGGCGCCGGAGACCCGTAAACTGGAGAAGTCGGAGGACGAGCCACCTTTGACTCTTCCCAAGCCTTCGCTCATTCCTCAGGAGGTTAAGATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000046876-'51-45,'51-43,58-45=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.657 C2=0.350
Domain overlap (PFAM):
C1:
NA
A:
PF125473=ATXN-1_C=WD(100=5.0),PF085177=AXH=PU(56.5=10.6)
C2:
PF085177=AXH=PD(41.7=27.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 21475249
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI002971; ELM sequence: AWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types