DreEX6073532 @ danRer10
Exon Skipping
Gene
ENSDARG00000061687 | atxn1a
Description
ataxin 1a [Source:ZFIN;Acc:ZDB-GENE-060503-759]
Coordinates
chr19:32814789-32874674:+
Coord C1 exon
chr19:32814789-32814889
Coord A exon
chr19:32869542-32871638
Coord C2 exon
chr19:32873916-32874674
Length
2097 bp
Sequences
Splice sites
3' ss Seq
GTTTCTTTATTATATTTCAGGTT
3' ss Score
10.14
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
GCTGTGCTGGAGGCCTGCGCTGAAACTACGAGCCGCGTTGGGATTGTAACGACTTCAATGGGCCACAACACTCACTGAAACACTGGAGGCTACTGAATGAG
Seq A exon
GTTCTTCCTGCAGTCCTGGAGACTCTCTCTCGGAAGGAAATGATTCCACATGAATTGCATGGACCGCTCTCCCGCAGCAGGTGTGACTTCAATTGCTTAAGACTGAAATCTGTGTCAATCCGACCATAGGCACAGGACACATCCCCTCTCACCACCACTCTCCTCTCTACCCCATTCCCATACTTGCTCCAAGCCAATCAGTAGGAGGGCACACTCTGTTAGCAAGACAAACAGAGACCAGGAGGGAGAGGAAAAGAGCCAAAAAAGGGGAAAGAAAAATCCGGAAAGAGTGGTTCAAGATTTTCAGACACCATGAAGTCAAACCAGGAGCGGAGCAATGAATGCCTGCCCCCAAAGAAGCGTGAAATCCCAGCAAGCACTCTGCCCTCAGAGGAGAAGCCCATGGTGATGGCCCCTGCCAATGAGAGCCAGCGTGGAGGGAACCTGGCTTGGCTTGCCAGTCTGGCCAGTGGGCATGACAAAGGCCGGCTGCACACCAGCACGTCTGCAGAATCAGATGGGCCTCAATATAAACCATTGTCAGCCATGGCTGAGAGCACACCTTCCTCGTCCACACACTCAACCAGAGCTCTATCTGCAGTCACCACCATACCTGCAGTGTACACATCACCTCTCTCCCATTCTCCTAGCGCAATCCAGTACACACCCCTCCCTCACAATATACACTTCATCAACCCTCCTTACTCTGCACCATACGCTGGCTACATTTCTCCACTAGCTCCCCCTTTAGCTGCCACCACTACCACACAACGTGAGATTTATGCCAGCTCCTCCAGTTCTCCAGCATCCAAAATTGATCAGCACCACCAATTGGGCCGTCCTCAAGGCCTGGTCACAACTGACAACACCTCTTCACCTCACTCCACTCAATATGTTCAAATTGCTGGTTCTCCACTAAGCATATCCCCTCGAACTGTTTCGTCACCGCATACACACATGCCCCTACATTTACATCCTCACCACACACTTCCCCTTAGCGGCCCTTCACAGGTCTTAGTCCCATACACAGAAAGTCTTTTACCCAAGAGGGAGGAGATGAGGACCAGGGAGTTGCTGAATGGAGAGCTGGAGAAGGACAGACGTTTTGGTCCATCTTCTGAGTCCAGTGCAGGGAAGCAGGGCAGCACTGCCAAAGGGGGTTCCTCTGCCCAGCAGCACCAGATCCACCAGCAGCAGAGCCCACGTCACTTTGAAGCTCGACATGTTGTGCTACCTGCCGAGTACACGCAGGACAGCACAGCCATGAGGACCTCATTGGTGCTGGTACCTAATAATCATAGCTCCACTAGTGCTGATTCTGGAGGTGCATCAGACAAGCTGCCTCCCTCGACATCCCACCATGAAAAAGGAGGGATTTGTGCTGGCAAACCTGTCTCCCGCAGTTCCTCCTTATCTTCCTCCCTTTCATTTGCTCTTCCCCCTCCACCTGTGGACAATCTTAAGGGAGCAGTTCCAGCGCAGTCTCCTCACGCAGTTATTCAGACCACACTTAACAGCACAGAGTCACTCTCTCTAAGCCTCCCCTCCACTAATTTCTACTCCACCCAGCAGCCTATCATTGGTTACTTTGCCGGCACAGGGCACCAGCAGCCTCTCAGCTACCACACCACCTTACCCCAGCACTTGGTCATCCCTGGAACTCAGCCGGTCATCATCCCAGTAAGTGGAACTGAAGCTACCGCTACATCAACTGCTGCACTGCCCCATGCTTTCGTCACCTCAACAGCCCCCAAAGTGGAGACTTTTGAGTCTCCGGCTCCATACCCCCACCCTGCCACAGCTATGGTTCAAGCCCAGTTGCATTTGCCTGTGGTTCCAGCAACTGCTGGCCTGCTGACAACTCCACCCCCACCCTCAGCTCCTTCAATGCCACCCTACTTCACCAAGGGCTCCATCATCCAATTGGCAGATGGGGAACTGAAGCGGGTGGAAGACCTGAAAACAGAGGATTTCATTCAGAGTGCTGAGATTAGCAACGAGCTGAAGATTGATTCCAGCACTGTAGAGCGCATCGACAGCAGTCATACAGCTAACTTTGCTATAATACAGTTTGCTGTAGGAGCGCAACGCTCACAG
Seq C2 exon
GTCAGTGTGGAGGTACTAGTAGAGTATCCTTTCTTTGTGTTCGGCCAGGGCTGGTCATCTTGTTGTCCGGATCGGACTACTCAGCTGCTCGAGCTGCCATGCACCAAGCTTTCAGTGGGTGACGTCTGCATCTCCCTCACCCTGAAGAACCTGAGGAACGGTTCCATCAAGAAGAGCCAGGGGCAAGTCTTGGATGCACCTGCACTCGGTCCACCTCTTAAATCACCAAAAGCACTCTCAAGTGGCGCACGAGGGGGTGTTCGGCACACAGAACAGGAAAATGGACTCGGGCAGTGTGCAGATCAAGGAAGTAGAGGCGGTCAAGGCAATAGAGAAAACGGAGAACTGAGGTTTGGTGAAAGGGACAACTGCAAAGCTCCAACACTCACAGAATCAGAGACCAGCAGTAAACCCACAGGTCGAAAAAGAAGGTGGTCCGCCCCTGAGGGTCGTAAAGTAGAAAATCCAGAAGGAGAGCCCCCTTTAACGTTCCCTAAGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000061687-'5-10,'5-8,10-10=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.657 C2=0.688
Domain overlap (PFAM):
C1:
NA
A:
PF125473=ATXN-1_C=WD(100=9.1),PF085177=AXH=PU(56.5=10.9),PF069718=Put_DNA-bind_N=WD(100=5.5)
C2:
PF085177=AXH=PD(41.7=25.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 21475249
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI002971; ELM sequence: AWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]