RnoEX6053319 @ rn6
Exon Skipping
Gene
ENSRNOG00000016998 | Atxn1
Description
ataxin 1 [Source:RGD Symbol;Acc:3624]
Coordinates
chr17:19417440-19533814:+
Coord C1 exon
chr17:19417440-19417560
Coord A exon
chr17:19518590-19520591
Coord C2 exon
chr17:19531955-19533814
Length
2002 bp
Sequences
Splice sites
3' ss Seq
TGCTCTCTTCTCCTTCTCAGAAT
3' ss Score
9.95
5' ss Seq
CAGGTAACC
5' ss Score
8.66
Exon sequences
Seq C1 exon
GTATTTCTAACCTCTCTGTGAAAGAAAGACAACACCAGAGCCTGGGCGGCCCAGTTGCTGAGGGAAGTTTCCATGGTGAAGTCTCAGGGAGGCTTCCTGGGAGCAGAACATAGTGAATGCT
Seq A exon
AATCCGGAGCTGCTACTGCCAGCCTAGAGAACCCACGGGGAGATGATTCCTCATGAAGGGCCTGGATCCCCTACAGAAATCCAATGTGACTCTCTGTTTATCAGACTAAAACCAGAGCCAGCCAGACAGTGAAACAGCCACCGTGGAGGGGGGACGGCGAAAAATGAAATCTAACCAAGAGCGGAGCAATGAATGCCTGCCTCCCAAGAAACGTGAGATCCCCGCCACCAGTCGGCCCTCCGAGGAGAAGGCCACTGCTCTGCCCAGCGACAACCACTGCGTGGAGGGTGTGGCATGGCTCCCCAGCACCCCTGGCAGCCGCGGCCACGGGGGTGGGCGGCACGGGCCAGCAGGGACTTCCGGGGAACATGGTTTACAAGGAATGGGTTTACATAAAGCACTGTCCGCAGGGCTGGATTACTCCCCACCCAGTGCCCCCAGGTCGGTCCCCACAGCCAACACGCTGCCCACCGTGTACCCTCCTCCTCAGTCAGGGACGCCGGTGTCTCCTGTGCAGTACGCCCACCTATCACATACCTTCCAGTTCATTGGGTCCTCCCAGTATAGTGGGCCTTACGCGGGCTTTATCCCTTCCCAGCTGATCTCCCCACCAGGCAACCCAGTCACCAGTGCGGTGGCCTCGGCTGCAGGGGCCACCACTCCATCACAGCGCTCCCAGCTGGAGGCATATTCCACCCTGCTGGCCAACATGGGCAGTCTGAGCCAGGCACCAGGACACAAGGTTGAGCCCCCTCCGCAGCAGCACCTCGGCAGGGCTGCGGGATTAGTCAACCCGGGGTCCCCTCCACCTACCCAGCAGAACCAGTACATTCACATTTCCAGCTCTCCACAGAGCTCCGGGCGGGCAACATCTCCACCCATCCCGGTCCACCTCCATCCCCATCAGACGATGATCCCGCACACGCTCACCCTGGGGCCTTCATCCCAGGTGGTCGTGCAATACAGTGACGCCGGAGGCCACTTTGTTCCTCGAGAGTCCACCAAAAAAGCAGAAAGCAGCAGGTTGCAGCAGGCTATGCAGGCCAAGGAGGTCCTCAATGGGGAGATGGAGAAAAGCCGGAGGTATGGGGCGTCATCTTCTGTGGAGCTGAGCCTGGGGAAGACGAGCAGCAAGTCAGTGCCTCACCCCTATGAGTCCAGGCATGTGGTGGTCCACCCGAGCCCAGCAGACTACAGCAGTCGTGATACCTCCGGGGTCCGTGGATCTGTGATGGTCCTGCCCAACAGCAGCACACCCTCAGCCGACCTGGAGACACAGCAGGCCACACATCGAGAGGCCTCCCCATCCACCCTCAATGACAAGAGCGGTTTGCACCTAGGGAAGCCCGGCCACAGGTCCTACGCGCTGTCCCCACACACGGTCATTCAGACCACACACAGCGCATCAGAGCCTCTCCCGGTGGGCCTACCAGCCACGGCCTTCTATGCTGGCGCTCAACCTCCTGTCATCGGCTATCTGAGTAGCCAGCAGCAAGCAATCACCTATGCTGGTGGTCTGCCCCAGCACCTGGTGATCCCAGGTACCCAGCCCCTGCTCATCCCAGTGGGCAGCCCTGACATGGACACACCTGGGGCAGCCTCGGCCATAGTGACGTCATCGCCCCAGTTTGCTGCAGTACCTCACACGTTTGTCACCACCGCCCTGCCCAAGAGCGAGAACTTCAACCCAGAGGCTCTGGTCACCCAGGCAGCCTACCCAGCCATGGTGCAGGCCCAGATCCACCTGCCGGTGGTACAGTCCGTGGCATCCCCTGCCGCGGCATCACCCACGCTGCCGCCATATTTCATGAAAGGCTCCATCATCCAGCTGGCCAACGGGGAGCTGAAGAAGGTAGAGGATCTGAAGACAGAGGATTTCATCCAGAGTGCAGAGATTAGCAATGACCTCAAGATCGACTCCAGTACTGTGGAGAGGATCGAGGACAGCCACAGCCCCGGTGTGGCCGTGATACAATTTGCTGTTGGTGAACACCGAGCCCAG
Seq C2 exon
GTCAGTGTCGAAGTTTTGGTAGAGTATCCTTTTTTTGTATTTGGACAGGGCTGGTCATCCTGCTGTCCCGAGCGGACCAGCCAGCTCTTTGATCTGCCGTGTTCCAAACTCTCCGTTGGGGACGTCTGCATCTCGCTCACCCTCAAGAACCTGAAGAATGGCTCTGTTAAAAAGGGCCAGCCCGTGGACCCTGCCAGTGCCCTGCTGAAGCACGCAAAGACCGACAGCCTGGCTGGCAGCAGACACAGATACGCCGAGCAGGAAAACGGAATCAACCAGGGGAGCGCCCAGGTGCTCTCTGAGAACGGCGAACTGAAGTTTCCAGAAAAAATTGGATTGCCTGCAGCACCCTTCCTCACCAAAATAGAACCGAGCAAGCCCACAGCCACGAGGAAGAGGAGGTGGTCGGCGCCGGAGACCCGTAAACTGGAGAAGTCGGAGGACGAGCCACCTTTGACTCTTCCCAAGCCTTCGCTCATTCCTCAGGAGGTTAAGATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000016998-'10-20,'10-19,18-20=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.659 C2=0.438
Domain overlap (PFAM):
C1:
NA
A:
PF125473=ATXN-1_C=WD(100=5.1),PF085177=AXH=PU(56.5=10.6)
C2:
PF085177=AXH=PD(41.7=27.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 21475249
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI002971; ELM sequence: AWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]