Special

MmuEX6058152 @ mm9

Exon Skipping

Gene
ENSMUSG00000046876 | Atxn1
Description
ataxin 1 [Source:MGI Symbol;Acc:MGI:104783]
Coordinates
chr13:45650262-45793314:-
Coord C1 exon
chr13:45793190-45793314
Coord A exon
chr13:45661942-45663949
Coord C2 exon
chr13:45650262-45652954
Length
2008 bp
Sequences
Splice sites
3' ss Seq
CTCCTCCTCCTCCTCCTCAGAAT
3' ss Score
9.62
5' ss Seq
CAGGTAACC
5' ss Score
8.66
Exon sequences
Seq C1 exon
GTATTTCTAACCTCTCTGCGAAAGAAAGAAAGACACCACCAGAACCTGGGCATCCCAGCTGCTGAGGGAAGTTTCCATGGTGAAGTCTCAGGGAGGCTTCCTGGGAGCAGAGCATAGTGAATGCT
Seq A exon
AATCCGGAGCTGCCACTGCCAGCCTAAAGAACCCACGGGGAGATGATTCCCCATGAAGGGCCTGGATCCCCTACAGAAATCCAATGTGACTCTCTGTTTATCAGACTAAAACCAGAGCCGGCCAGCCAGTGAAACAGCCACCGTGGAGGGGGGACGGCGAAAAATGAAATCCAACCAAGAGCGGAGCAACGAATGCCTGCCTCCCAAGAAACGTGAGATCCCCGCCACCAGCCGGCCCTCGGAGGAGAAGGCCACTGCTCTGCCCAGCGACAACCACTGCGTGGAGGGTGTGGCCTGGCTCCCCAGCACCCCTGGCATCCGCGGCCATGGGGGTGGGCGGCACGGGTCAGCAGGGACTTCCGGGGAGCATGGTTTACAAGGAATGGGTTTACATAAAGCACTGTCCGCAGGGCTGGATTACTCCCCACCCAGTGCCCCCAGGTCAGTCCCCACAGCCAACACGCTGCCCACCGTGTACCCTCCTCCTCAGTCAGGGACCCCGGTGTCTCCTGTGCAGTACGCCCACCTTTCGCATACCTTCCAGTTCATTGGGTCCTCCCAATACAGTGGGCCTTACGCGGGCTTTATCCCTTCCCAGCTGATCTCCCCATCAGGCAACCCGGTCACCAGTGCAGTAGCCTCAGCTGCAGGGGCCACCACTCCATCACAGCGCTCCCAGCTGGAGGCTTATTCCACCCTGCTGGCCAACATGGGCAGTCTGAGCCAGGCACCAGGACATAAGGTTGAGCCCCCTCCGCAGCAGCACCTCAGCAGGGCTGCAGGATTAGTCAACCCGGGGTCCCCTCCTCCACCCACCCAGCAGAACCAGTACATCCATATTTCCAGCTCTCCACAGAGCTCCGGGCGGGCGACATCTCCCCCACCCATCCCGGTCCACCTCCATCCCCATCAGACGATGATCCCGCACACACTCACCCTGGGGCCTTCATCCCAGGTGGTTGTGCAATATAGTGATGCCGGAGGCCACTTTGTTCCTCGAGAGTCCACCAAAAAAGCCGAGAGCAGCAGGTTGCAGCAGGCTATGCAAGCCAAGGAAGTCCTGAATGGGGAGATGGAGAAAAGCCGGAGGTATGGGGCATCATCTTCTGTGGAGCTGAGCCTAGGCAAGGCAAGCAGTAAGTCAGTGCCTCATCCCTATGAGTCCAGGCATGTGGTGGTCCACCCAAGCCCAGCAGACTACAGCAGTCGTGATACCTCCGGGGTCCGTGGATCTGTGATGGTTCTGCCTAATAGCAGCACACCCTCAGCCGACCTGGAGGCCCAGCAGACCACGCATCGAGAGGCCTCCCCATCCACCCTCAATGACAAGAGCGGCCTGCACCTAGGGAAGCCGGGCCACAGGTCTTATGCGCTGTCCCCCCACACGGTCATTCAGACCACACACAGTGCATCAGAGCCTCTCCCGGTGGGCCTACCAGCCACGGCCTTCTACGCTGGCACTCAACCTCCTGTCATCGGCTACCTGAGCGGCCAGCAGCAAGCAATCACCTATGCTGGTGGTCTGCCGCAGCACCTGGTGATCCCAGGTAACCAGCCCCTGCTCATCCCGGTGGGCAGCCCTGACATGGACACGCCTGGGGCAGCCTCGGCCATCGTGACGTCATCACCCCAGTTTGCTGCAGTACCTCACACGTTTGTCACCACCGCCCTGCCCAAGAGCGAGAACTTCAACCCAGAGGCTCTGGTCACCCAGGCTGCCTACCCAGCCATGGTGCAGGCCCAGATCCACCTGCCGGTGGTGCAGTCCGTGGCGTCCCCCACCACGGCGTCTCCCACGCTGCCGCCATATTTCATGAAAGGCTCCATCATCCAGCTGGCCAACGGGGAGCTGAAGAAGGTGGAGGACCTGAAGACGGAGGATTTCATCCAGAGTGCAGAGATTAGCAATGACCTCAAGATCGACTCCAGTACTGTGGAGAGAATCGAGGAGAGCCACAGCCCCGGGGTGGCCGTGATACAGTTTGCTGTTGGTGAACACCGAGCCCAG
Seq C2 exon
GTCAGTGTCGAAGTCTTGGTAGAGTATCCTTTTTTTGTATTTGGACAGGGCTGGTCATCCTGCTGTCCTGAGCGGACCAGCCAGCTCTTTGATCTGCCGTGTTCCAAACTCTCTGTTGGGGACGTCTGCATCTCGCTCACCCTCAAGAACCTGAAGAATGGCTCTGTTAAAAAGGGCCAGCCTGTGGACCCTGCCAGCGTCCTGCTGAAGCAGGCAAAGACCGACAGCCTGGCTGGCAGCAGACACAGATACGCGGAGCAGGAAAACGGAATCAACCAGGGAAGCGCCCAGGTGCTCTCTGAGAATGGCGAACTGAAGTTTCCAGAAAAAATAGGATTGCCTGCAGCACCCTTCCTCAGCAAAATAGAACCGAGCAAACCCACAGCCACGAGGAAGAGGAGGTGGTCGGCGCCGGAGACCCGTAAACTGGAGAAGTCGGAGGACGAGCCACCTTTGACTCTTCCCAAGCCTTCGCTCATTCCTCAGGAGGTTAAGATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000046876-'8-13,'8-12,11-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=NA A=0.657 C2=0.352
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NA

							
A:
PF125473=ATXN-1_C=WD(100=5.0),PF085177=AXH=PU(56.5=10.6),PF069718=Put_DNA-bind_N=WD(100=5.0)

							
C2:
PF085177=AXH=PD(41.7=27.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000089217





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000129890
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr6:16326394-16328470 
HIGH PSI
HsaEX0007247
(ATXN1)
Human
(hg19)
chr6:16326625-16328701 
HIGH PSI
HsaEX0007247
(ATXN1)
Rat
(rn6)
chr17:19518590-19520591 
HIGH PSI
RnoEX6053319
(Atxn1)
Cow
(bosTau6)
chr23:40588388-40590470 
Chicken
(galGal4)
chr2:61661702-61663727 
Chicken
(galGal3)
chr2:62708295-62710320 
Zebrafish
(danRer10)
chr19:32869542-32871638 
HIGH PSI
DreEX6073532
(atxn1a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 1 annotated functions for this event 


PMID: 21475249
HsaEX0007247
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI002971; ELM sequence: AWLP; Overlap: FULL


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"