DreEX6048663 @ danRer10
Exon Skipping
Gene
ENSDARG00000028507 | itgb4
Description
integrin, beta 4 [Source:ZFIN;Acc:ZDB-GENE-030131-7209]
Coordinates
chr8:13110809-13115993:+
Coord C1 exon
chr8:13110809-13110958
Coord A exon
chr8:13113736-13113924
Coord C2 exon
chr8:13115838-13115993
Length
189 bp
Sequences
Splice sites
3' ss Seq
GTATTGTGTTTGTCTGTTAGGTG
3' ss Score
9.31
5' ss Seq
CCGGTGAGA
5' ss Score
8.72
Exon sequences
Seq C1 exon
AATCGCGCTTCACCCCGGGTGTTCCCGCGACTCCCAGCAGACTGGTGTTTTCAGCTCTGGGCCACACGGCTCTCAAAGTGAGCTGGCAGGAGCCACACTGCGAGTCTGATGTACTGGGATACTGCGTCCTTTACCAGCTCATCAATGGAG
Seq A exon
GTGACGTAAAACGTATCGAGGTGAACAATCCTGCTCAGAACTCAGTGCTGGTTCAGGATCTCCTGCCTAACCAGTCCTACATCTTCAAAGTCAAAGCACAGAGTCGAGAGGGCTGGGGTCCTGAGAGAGAGGGCGTCATTACCATTGAGTCCAACGTCGACCCCAAGAGTCCACTGAGCCCAGTGCCCG
Seq C2 exon
GGTCTCCGTTCACTCTCAGCACTCCCAGCGCTCCAGGACCTCTGATCTTCACAGCGTTACGTCCAGATACACTGCAGCTGAGCTGGGAGAAACCCCGAAAACCCAACGGAGACATCCTGGGATACGTGGTGACCTGCGAACAGCTGCATGGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000028507-'40-44,'40-43,41-44=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.033 A=0.312 C2=0.208
Domain overlap (PFAM):
C1:
PF0004116=fn3=PU(48.8=80.4)
A:
PF0004116=fn3=PD(50.0=65.6)
C2:
PF0004116=fn3=PU(50.0=81.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGGTGTTTTCAGCTCTGGG
R:
GGTCACCACGTATCCCAGGAT
Band lengths:
244-433
Functional annotations
There are 1 annotated functions for this event
PMID: 11044453
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, mutation analysis, pull down. ELM ID: ELMI001551; ELM sequence: LLPNHSY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]