RnoEX0045231 @ rn6
Exon Skipping
Gene
ENSRNOG00000005580 | Itgb4
Description
integrin subunit beta 4 [Source:RGD Symbol;Acc:2928]
Coordinates
chr10:104558184-104559239:+
Coord C1 exon
chr10:104558184-104558333
Coord A exon
chr10:104558777-104558965
Coord C2 exon
chr10:104559084-104559239
Length
189 bp
Sequences
Splice sites
3' ss Seq
TTCCGCCCTCCACCTCTCAGGCG
3' ss Score
8.68
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
ATTCCCGTGGGGCTATGGGTGTGCCCGACACACCCACTCGGCTGGTGTTCTCCGCCCTGGGGCCCACATCTCTGAAGGTGAGCTGGCAGGAGCCACAGTGTGATCGAGCACTGCTGGGCTACAGCGTGGAATACCAGCTACTCAACGGCG
Seq A exon
GCGAGATGCATCGGCTCAACATCCCTAACCCTGGCCAAACCTCTGTGGTGGTAGAGGATCTCCTGCCTAACCACTCCTATGTGTTCCGGGTGCGGGCACAAAGCCAGGAGGGCTGGGGCCGGGAGCGAGAGGGTGTCATCACCATCGAGTCCCAGGTGCACCCGCAGAGCCCTCTCTGCCCCCTGCCAG
Seq C2 exon
GCTCCGCCTTCACCTTGAGCACCCCCAGCGCCCCAGGCCCCCTGGTGTTCACTGCCCTAAGCCCAGACTCTCTGCAGCTGAGCTGGGAGCGCCCAAGAAGGCCCAACGGAGATATCCTTGGCTACCTGGTGACCTGTGAGATGGCCCAAGGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000005580-'51-54,'51-53,52-54
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.196 A=0.312 C2=0.226
Domain overlap (PFAM):
C1:
PF0004116=fn3=PU(48.8=80.4)
A:
PF0004116=fn3=PD(50.0=65.6)
C2:
PF0004116=fn3=PU(49.4=81.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCACATCTCTGAAGGTGAGC
R:
CTCCTCCTTGGGCCATCTCA
Band lengths:
244-433
Functional annotations
There are 1 annotated functions for this event
PMID: 11044453
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, mutation analysis, pull down. ELM ID: ELMI001551; ELM sequence: LLPNHSY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]