DreEX6048926 @ danRer10
Exon Skipping
Gene
ENSDARG00000013841 | abl2
Description
c-abl oncogene 2, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-020809-2]
Coordinates
chr8:14923499-14932801:+
Coord C1 exon
chr8:14923499-14923663
Coord A exon
chr8:14930285-14930580
Coord C2 exon
chr8:14932529-14932801
Length
296 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTTTGGGATTGCAGGAG
3' ss Score
6.16
5' ss Seq
AAGGTATAA
5' ss Score
7.08
Exon sequences
Seq C1 exon
AAGCCCTGCACAGGCCGTTTGGACTGGACTCGACGGCGCTGACGGAGGCGGTGCGCTGGAGCTCCAAGGAGAATCTGCTGGGTGCTGCTGAAAGTGACCCCAACCTTTTTGTGGCACTTTACGACTTTGTTGCCAGTGGTGACAACACACTAAGCATCACGAAAG
Seq A exon
GAGAGAAGCTGCGAGTGTTGGGTTATAACCAGAATGGAGAATGGAGTGAAGTCCGCTCAAAGAACGGCCAGGGCTGGGTACCCAGTAACTACATCACCCCCGTAAACAGTCTGGAGAAGCACAGCTGGTACCATGGGCCCGTGTCCCGCAGCGCTGCCGAGTACCTGCTCAGTAGCTTGATCAACGGCAGCTTCCTGGTGCGGGAAAGCGAGAGCAGCCCCGGCCAGCTCTCCATCTCTCTTCGCTATGAGGGACGGGTCTATCATTACCGCATCAACACGGCCTCTGATGGAAAG
Seq C2 exon
GTCTATGTGACAGCAGAGAGTCGTTTCAGCACGTTAGCTGAGCTGGTTCATCATCATTCCACAGTTGCGGATGGACTGGTAACCACTCTGCATTATCCTGCTCCCAAATGCAACAAGCCCACCGTCTACGGCGTCTCTCCCATCCACGACAAGTGGGAGATGGAGCGCACCGACATCACCATGAAGCACAAATTGGGTGGAGGACAGTACGGAGAGGTGTACGTTGGAGTTTGGAAAAAGTACAACCTCACTGTAGCTGTAAAAACACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013841-'4-6,'4-4,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.012 A=0.010 C2=0.000
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PU(38.3=32.1)
A:
PF0001823=SH3_1=PD(59.6=28.3),PF0001719=SH2=PU(73.7=56.6)
C2:
PF0001719=SH2=PD(23.7=19.8),PF0771412=Pkinase_Tyr=PU(12.7=35.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAAGGAGAATCTGCTGGGT
R:
GTGCTTCATGGTGATGTCGGT
Band lengths:
292-588
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]