RnoEX0005535 @ rn6
Exon Skipping
Gene
ENSRNOG00000004305 | Abl2
Description
ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:RGD Symbol;Acc:1590898]
Coordinates
chr13:74221142-74229071:+
Coord C1 exon
chr13:74221142-74221312
Coord A exon
chr13:74224636-74224931
Coord C2 exon
chr13:74228799-74229071
Length
296 bp
Sequences
Splice sites
3' ss Seq
TTTCATTCTATGATGGCTAGGTG
3' ss Score
4.63
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
Exon sequences
Seq C1 exon
AAGTTTTGCACCGCCCCTTTGGTTGTGACGCTGAATCTCAGGCACTGAATGAAGCTATCAGGTGGAGCTCCAAGGAGAACTTGCTGGGCGCCACTGAGAGCGACCCTAATCTCTTTGTTGCACTTTATGACTTTGTGGCAAGTGGCGATAACACACTCAGCATCACCAAAG
Seq A exon
GTGAAAAGCTACGAGTCCTTGGTTACAACCAAAATGGTGAATGGAGTGAAGTTCGCTCCAAGAATGGGCAGGGTTGGGTGCCCAGCAACTACATCACTCCAGTCAACAGCCTGGAGAAACATTCCTGGTACCATGGGCCTGTGTCCCGCAGTGCAGCGGAGTATCTCCTCAGCAGCCTTATCAATGGCAGTTTCCTGGTGCGAGAGAGTGAGAGCAGCCCTGGGCAGCTGTCCATCTCTCTCAGATATGAGGGACGTGTGTATCACTACAGGATCAATACCACCACAGACAGCAAG
Seq C2 exon
GTGTACGTGACTGCCGAGAGCCGCTTCAGCACCTTAGCAGAGCTTGTTCACCACCACTCCACAGTCGCTGATGGGCTAGTGACCACGCTACATTACCCAGCACCCAAGTGCAACAAGCCAACCGTCTACGGTGTGTCTCCTATCCACGACAAGTGGGAGATGGAGCGCACAGATATCACCATGAAGCACAAGCTTGGGGGCGGCCAGTATGGAGAGGTTTACGTTGGCGTCTGGAAGAAATACAGCCTTACAGTTGCTGTGAAAACACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000004305-'4-7,'4-4,6-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.112 A=0.010 C2=0.000
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PU(38.3=31.0)
A:
PF0001823=SH3_1=PD(59.6=28.3),PF0001719=SH2=PU(73.7=56.6)
C2:
PF0001719=SH2=PD(23.7=19.8),PF0771412=Pkinase_Tyr=PU(12.7=35.2)
Main Skipping Isoform:
ENSRNOT00000059524fB418
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGTGACGCTGAATCTCAGGC
R:
TCGTGGATAGGAGACACACCG
Band lengths:
298-594
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]