DreEX6050523 @ danRer10
Exon Skipping
Gene
ENSDARG00000042329 | BCR (1 of 2)
Description
breakpoint cluster region [Source:HGNC Symbol;Acc:HGNC:1014]
Coordinates
chr8:30551604-30561344:+
Coord C1 exon
chr8:30551604-30551744
Coord A exon
chr8:30560929-30561050
Coord C2 exon
chr8:30561179-30561344
Length
122 bp
Sequences
Splice sites
3' ss Seq
TCTTATTCTTGTCTTTGAAGAAT
3' ss Score
7.82
5' ss Seq
AGGGTAAGA
5' ss Score
9.21
Exon sequences
Seq C1 exon
GACCTCCTGAAGCACACCCCATCCAGTCATCCAGATTACCCTCTGCTGCAGGACGCCCTCCGCATTTCCCAGAACTTCCTCTCCAGCATTAATGAAGAGATCACACCCCGCCGTCAGTCCATGACAGTGAAGAAAGGAGAG
Seq A exon
AATCGACAGCTTCTTCGAGACCAGTTTATGGTGGAGTTAGTAGAAGGTGCACGAAAACTGCGACACGTCTTCCTCTTTACCGACATTCTGCTCTGCGCTAAATTGAAGAAACAAACTGGAGG
Seq C2 exon
GAAGGGGCAGCAGTATGACTGTAAGTGGTATATCCCGCTAGCGGACGTCACCTTCCAGACCATCGATGAGTCTGAGTCCTCGCCTGTTCCACAGATACCAGAAGAGGAGATTGATGCTTTGAAGGTCAAGATCTCTCAGATCAAAAACGAGATCCAGCGGGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000042329-'11-12,'11-11,12-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.213 A=0.000 C2=0.054
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=PD(16.7=66.0),PF0016924=PH=PU(1.8=6.4)
A:
PF0016924=PH=FE(24.4=100)
C2:
PF0016924=PH=FE(33.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGCATTTCCCAGAACTTCCT
R:
CCCGCTGGATCTCGTTTTTGA
Band lengths:
243-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]