DreEX6064154 @ danRer10
Exon Skipping
Gene
ENSDARG00000077231 | vwf
Description
von Willebrand factor [Source:ZFIN;Acc:ZDB-GENE-070103-1]
Coordinates
chr18:7220745-7223258:+
Coord C1 exon
chr18:7220745-7220901
Coord A exon
chr18:7222883-7223038
Coord C2 exon
chr18:7223123-7223258
Length
156 bp
Sequences
Splice sites
3' ss Seq
ACTGATGGTATTTTTCTCAGCTC
3' ss Score
5.38
5' ss Seq
CAGGTACAG
5' ss Score
8.68
Exon sequences
Seq C1 exon
GTGGACCCGGAGCCGTACTGGGACATCTGCACTCAAGACACCTGCTCATGCCCGTCTGTTGGGGACTGTGCCTGTTTCTGTAACACTATCGCCGCTTATGCTCACGAATGTGCTCAGAAGGGGCTGCCGGTCAACTGGAGGTCCAACGACTTGTGCC
Seq A exon
CTCTGAGCTGTGAGGATCTGAATAAGGAGTCTGGGGTTCAGTGTGAGTGGAGATATAACACCTGTGCTAGCGCCTGCCCATCCACCTGCCAGCACCCGGAGCCTCTGAGCTGCCCCATCAGCTGTGTGGAGGGATGCCATGCTGTCTGTCCGCCAG
Seq C2 exon
GGCACCTTTTAGACGAGGTGCTGAGAAAGTGTGTGGAGCCATCTCAGTGTCAGGTGTGTGTTCACGATGGACAGAGAGTCTCGCATGGAAAACAGTTCATCCTCAACCATGAAGATCCACGTCTCTGCCAGATATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000077231-'23-28,'23-27,25-28=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF087426=C8=FE(69.3=100)
A:
PF087426=C8=PD(0.1=0.0),PF0182612=TIL=PU(69.6=73.6)
C2:
PF0182612=TIL=PD(28.6=34.8)
Main Skipping Isoform:
ENSDART00000114690fB7071
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCAAGACACCTGCTCATGCC
R:
TCTGGCAGAGACGTGGATCTT
Band lengths:
258-414
Functional annotations
There are 1 annotated functions for this event
PMID: 3524673
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: protein cleavage. ELM ID: ELMI000123; ELM sequence: NSC; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]