MmuEX6007125 @ mm10
Exon Skipping
Gene
ENSMUSG00000001930 | Vwf
Description
Von Willebrand factor [Source:MGI Symbol;Acc:MGI:98941]
Coordinates
chr6:125637380-125639398:+
Coord C1 exon
chr6:125637380-125637536
Coord A exon
chr6:125637967-125638125
Coord C2 exon
chr6:125639263-125639398
Length
159 bp
Sequences
Splice sites
3' ss Seq
CTTTTCTTTTGTCTCCACAGCCC
3' ss Score
12.61
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GTGGACCCTGAGCCATACCTGGACATCTGTATTTATGACACTTGCTCCTGTGAGTCCATCGGGGACTGCGCCTGTTTCTGTGACACCATTGCTGCCTATGCCCACGTGTGTGCCCAGCATGGCCAGGTGGTAGCCTGGAGGACACCCACACTGTGCC
Seq A exon
CCCAGAGCTGTGAAGAAAAGAATGTTCGGGAAAATGGCTATGAGTGTGAGTGGCGTTATAACAGCTGTGCGCCTGCTTGCCCAGTCACGTGTCAGCACCCTGAGCCTCTGGCTTGCCCTGTGCAGTGTGTGGAGGGTTGTCATGCACATTGCCCTCCAG
Seq C2 exon
GGAGAATCCTGGATGAACTTCTGCAGACCTGCGTAGACCCCCAAGACTGCCCCGTGTGTGAGGTGGCTGGTCGGCGCTTGGCTCCTGGAAAGAAAATCACCTTGAGTCCTGATGACCCTGCACACTGTCAGAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001930-'46-55,'46-47,51-55=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.022
Domain overlap (PFAM):
C1:
PF087426=C8=FE(69.3=100)
A:
PF087426=C8=PD(0.1=0.0),PF0182612=TIL=PU(69.6=72.2)
C2:
PF0182612=TIL=PD(28.6=34.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGCTCCTGTGAGTCCATCG
R:
GACAGTGTGCAGGGTCATCAG
Band lengths:
246-405
Functional annotations
There are 1 annotated functions for this event
PMID: 3524673
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: protein cleavage. ELM ID: ELMI000123; ELM sequence: NSC; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types