DreEX6096485 @ danRer10
Exon Skipping
Gene
ENSDARG00000068468 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr24:39604347-39611004:+
Coord C1 exon
chr24:39604347-39606488
Coord A exon
chr24:39606896-39607121
Coord C2 exon
chr24:39610760-39611004
Length
226 bp
Sequences
Splice sites
3' ss Seq
GCACTCTTTTTTTTGCTCAGGAC
3' ss Score
7.93
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
Exon sequences
Seq C1 exon
GAAGGACAAGCTGCTGTTCTCTTTGCTGTTGACTGTAGGCATCATGCAGGGCAAAGGTCAGGTGGACGACATCGTCTGGCGTTTCCTCCTCACAGGAGGTGTTGCACTAGAAAACCCACACCCCAACCCAGCTCCAGAGTGGCTTTCAGACAAATCTTGGTCTGAAGTGGTGCGGGCTTCCCAACTTTCCCGCCTTGAAGGATTATTTGAGCATGTGCAGGAGAACATTGCACTGTGGAAGCAGATTTATGACTCTGGCCATCCACAGGACGAGGAGTTACCTGGAAAGTGGCATACAGTCGTGGGCATGGAGCGCATGGTGGTCCTGCGTTGCTTCAGACCAGATAAACTGGTGCCAGCAGTACAGAAGTTCATTGTGGACAACATCGGTCGAGCATACATCGAGCCACCGACCTTTGACTTGGCGGAGAGCTACAGCGACTCCAACTGCTGTTCGCCACTCATCTTCGTCCTCTCTCCAGGATCAGACCCCACGGCAG
Seq A exon
GACTACTGAAGTTTGCGGATGATTTGGGTATGGGCGGCAGTAGGACCCAGACAATCTCTCTGGGTCAGGGTCAAGGGCCTGTAGCTGAGCAGCTGATCAAGGCCGCACTGAGCGTCGGCCACTGGGTGGTGCTGCAGAACTGCCACCTCGCAACCAGCTGGATGCCAACCTTAGAGAAGATCTGTGAGGAGGTCATCACACCTGAAAACACACACACCAGCTTCAG
Seq C2 exon
GTTGTGGTTGACCAGTCAACCCTCAGACAAGTTTCCGGTGAGTGTTTTGCAGAATGGCGTGAAGATGACAAACGAGCCTCCGAAAGGCCTGAGGGCAAATCTACTTCGTTCTTACCTCAGCGACCCCATCTCAGACCCCACCTTCTTCAACAGCTCCGCTAGGCAGGAGATCTGGCAGAAGCTGCTGTTCGGCCTCTGTTTCTTCCACGCTCTGGTACAAGAGAGGAGAACATTCGGCCCACTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000068468-'46-48,'46-47,47-48=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=0.079 C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(59.1=29.1),PF083176=Spc7=WD(100=22.2),PF127812=AAA_9=WD(100=32.2),PF0302810=Dynein_heavy=PU(18.4=18.3)
A:
PF0302810=Dynein_heavy=FE(10.5=100)
C2:
PF0302810=Dynein_heavy=FE(11.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGTGCCAGCAGTACAGAAG
R:
AGAAGGTGGGGTCTGAGATGG
Band lengths:
297-523
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]