HsaEX6042679 @ hg19
Exon Skipping
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:20966135-20976747:-
Coord C1 exon
chr16:20974606-20976747
Coord A exon
chr16:20970501-20970726
Coord C2 exon
chr16:20966135-20966379
Length
226 bp
Sequences
Splice sites
3' ss Seq
TCCTTTCTTCCTGGTCTCAGGCC
3' ss Score
9.08
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GAAGGACAAGCTACTCTTCTCTCTCCTCCTGACCATCGGCATCATGAAACAGAAGAAGGAAATTACGGAGGAGGTGTGGTACTTCCTTCTCACTGGAGGCATCGCACTGGATAACCCCTACCCCAATCCAGCTCCCCAATGGCTGTCTGAGAAGGCATGGGCAGAGATTGTCCGTGCATCTGCCTTACCCAAACTGCATGGCCTGATGGAGCATTTGGAACAGAACCTGGGTGAATGGAAGCTGATCTATGACTCGGCCTGGCCCCATGAGGAGCAACTCCCTGGGTCTTGGAAGTTCTCTCAAGGATTGGAGAAGATGGTGATCCTTCGATGTTTGCGGCCTGACAAAATGGTGCCAGCGGTCCGGGAGTTCATTGCTGAACATATGGGAAAGCTGTATATCGAAGCCCCTACGTTCGATCTCCAGGGATCCTACAATGATTCCAGCTGCTGTGCGCCTTTGATTTTTGTGTTGTCTCCAAGTGCAGACCCAATGGCAG
Seq A exon
GCCTGCTGAAGTTTGCTGATGATCTTGGTATGGGAGGTACCAGAACACAGACCATCTCCCTTGGCCAAGGCCAAGGCCCTATTGCTGCCAAAATGATCAACAATGCCATCAAAGACGGGACCTGGGTGGTCTTACAGAACTGCCACCTGGCCGCAAGCTGGATGCCTACCCTGGAGAAGATTTGTGAGGAGGTGATTGTTCCTGAGAGCACCAATGCCAGATTCAG
Seq C2 exon
ACTCTGGCTAACCAGCTATCCATCAGAGAAGTTTCCAGTCAGCATTCTCCAGAATGGAATCAAAATGACCAATGAGCCCCCCAAAGGGCTCCGGGCCAACCTGTTGCGCTCCTACCTCAATGACCCCATCTCAGATCCTGTGTTCTTCCAAAGCTGTGCAAAGGCGGTGATGTGGCAAAAGATGTTATTTGGCCTTTGTTTCTTCCACGCCGTTGTTCAAGAGAGAAGAAACTTCGGCCCCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-'57-59,'57-58,58-59=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.004 A=0.026 C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(59.0=29.0),PF127812=AAA_9=WD(100=32.3),PF0302810=Dynein_heavy=PU(18.4=18.3)
A:
PF0302810=Dynein_heavy=FE(10.5=100)
C2:
PF0302810=Dynein_heavy=FE(11.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTTCGATCTCCAGGGATCCT
R:
TGAACAACGGCGTGGAAGAAA
Band lengths:
306-532
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)