MmuEX0015002 @ mm10
Exon Skipping
Gene
ENSMUSG00000052273 | Dnah3
Description
dynein, axonemal, heavy chain 3 [Source:MGI Symbol;Acc:MGI:2683040]
Coordinates
chr7:119938789-119952735:-
Coord C1 exon
chr7:119950594-119952735
Coord A exon
chr7:119943461-119943686
Coord C2 exon
chr7:119938789-119939033
Length
226 bp
Sequences
Splice sites
3' ss Seq
ACTTTTCTTCCTGGTCTCAGGTC
3' ss Score
9.86
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GAAGGACAAGCTACTTTTCTCCCTCCTTCTGACCGTTGGCCTCTTGAAGGAAAGAAAGGCAATTGATGAGGAAGTTTGGTACTTCCTTTTAACTGGAGGTGTGGCCTTGGACAATCCTTTCCCCAACCCAGCTCCAGAATGGTTATCAGAGAAGTCATGGGGTGAGATTGTTCGAGCTTCCTCCTTACAGAAACTAAAGGGTCTGATGGAAGATGTCATGCAAAATATCAAAGTATGGAAGGACATCTATGACTCAGCCTGGCCACATGAAGAGTCACTACCTTCACCTTGGTTTTTCCTTCAAACACTGGAAAAGATAGCAATCCTTCGATGTTTGCGGCCCGACAAGATAGTCCCAGCCATTCAAAACTTCATCTGTGAAACCATGGGAAAGATATTCATCGAAGCCCCAACCTTTGATCTCCAGGGATCCTACGGTGATTCCAGTTGCTGCGTACCATTGATTTTCATACTGTCTCCAGGTGCAGACCCAATGGCAG
Seq A exon
GTCTGCTGAAGTTTGCTGATGATGTTAGCATGGGAGGCACTAAAACACAGACCATCTCCCTTGGTCAAGGCCAAGGTCCTATTGCTGCCAATATGATCAACAAAGCCATCCATGAAGGGACCTGGGTGGTCCTACAGAACTGCCACCTGGCTACAAGCTGGATGCCAGCGTTAGAGAAGATTTGTGAGGAGGTGATTGTCCCTGAGAACACCAACTCAGAGTTCAG
Seq C2 exon
GCTCTGGCTAACTAGCTATCCATCAGAGAAGTTTCCCGTCAGCATTCTCCAGAATGGGATCAAAATGACCAACGAGCCCCCCAAAGGACTTAGGGCCAACCTTCTGCGTTCCTACCTCAATGACCCAATCTCAGACCCTTTGTTCTTCCAGAGCTGTACAAAGCCAGTTATATGGCAGAAACTGTTGTTTGGGCTTTGCTTCTTCCATGCCATTGTCCAGGAGAGGAGGAACTATGGAGCCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052273-'66-69,'66-67,67-69
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.004 A=0.026 C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(59.0=29.0),PF127812=AAA_9=WD(100=32.3),PF0302810=Dynein_heavy=PU(18.4=18.3)
A:
PF0302810=Dynein_heavy=FE(10.5=100)
C2:
PF0302810=Dynein_heavy=FE(11.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACGGTGATTCCAGTTGCTGC
R:
TCCTCTCCTGGACAATGGCAT
Band lengths:
294-520
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types