DreINT0096582 @ danRer10
Intron Retention
Gene
ENSDARG00000045401 | mllt10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:ZFIN;Acc:ZDB-GENE-041114-176]
Coordinates
chr24:17021132-17021761:+
Coord C1 exon
chr24:17021132-17021235
Coord A exon
chr24:17021236-17021667
Coord C2 exon
chr24:17021668-17021761
Length
432 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
3' ss Seq
CTGTCTTTGAATGAATGTAGCGC
3' ss Score
4.48
Exon sequences
Seq C1 exon
ACATGCTACATCTGTGAGGAACAGGGTCGTGAGAGCAAAGCTGCTACTGGAGCCTGCATGACATGCAATAAACATGGCTGCAGACAGGCCTTTCATGTCACATG
Seq A exon
GTAAGTTGCTGAACCTTTATATTTCAACTAAATGTTCTTATAAGTATCCTTAAAAGAACAGATCACCCAAAAATCTAAATTTACACAGCGTTCACTCACATTCAAGTGGTTCCAGACCTTTTTCGTTCTCATTTCTTTGCTGAACAAAAAAGAAGAGATTTTGAAGAATGCTGTTTGCATTGACATCTATAGTAGAAATGTAAAACGTCTTCAACACATACAAATATAGGGTGGGTAACTGATGACAATGTCTATTTTTGGGTGATCTTTTTAATTATGGTATATATTAAATGGAGAACAGGATTTAATACAGTAAACCTAAATTAAATGACTTTATATGTACAAATGTTGTGTGAATGTCATTTATTTAAATATGCATTGTGTTCAGCCTTTTGAAAGTTTTTTTTTTTATCTGTCTTTGAATGAATGTAG
Seq C2 exon
CGCTCAGTTAGCTGGGTTGTTGTGTGAAGAACAGGGTTCAGATGCTGATAATGTGAAATACTGTGGATACTGCAAGTACCATTACAACAAACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000045401:ENSDART00000148756:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF138321=zf-HC5HC2H_2=FE(28.8=100),PF0465211=DUF605=PU(3.2=17.1)
A:
NA
C2:
PF138321=zf-HC5HC2H_2=PD(22.9=84.4),PF0465211=DUF605=FE(16.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATGCTACATCTGTGAGGAACA
R:
CAGTTTGTTGTAATGGTACTTGCAGT
Band lengths:
198-630
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]