MmuINT0099340 @ mm10
Intron Retention
Gene
ENSMUSG00000026743 | Mllt10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:MGI Symbol;Acc:MGI:1329038]
Coordinates
chr2:18122245-18123812:+
Coord C1 exon
chr2:18122245-18122348
Coord A exon
chr2:18122349-18123718
Coord C2 exon
chr2:18123719-18123812
Length
1370 bp
Sequences
Splice sites
5' ss Seq
ATGGTATGT
5' ss Score
8.35
3' ss Seq
CCTTGGTGTTCATTTTGCAGTGC
3' ss Score
8.2
Exon sequences
Seq C1 exon
ACTTGCTATATATGTGATGAACAAGGACGAGAAAGCAAAGCAGCCACTGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATG
Seq A exon
GTATGTTTCCCTCATTGTAAAGAAATAAAATCGGCAAACACATTACATAACATGAAATTAAATATCTATCTACAGTTTTTCTGTTCAGTGCTGAGGATCAACTCAGTACCTGTGGATGTTGTAAAAGTGTTGACCCAGCTACATCCCAGTGCTCTTTTATTGTTTTTGACCAAAAAAGCATATGTTGATCTTGTTTATTGTGCTGTGATTTTGAAGCATGTAAGAATTGCCAAGAATTTTTCCTTTTAAGTTGATGAAGTTTTACCCAGCCCTGGTGGTAAAATCATGTAATACCTGCTACTCAGGAGTTATAGGCAGGGAAATTGCCACTTCAAGGCCTGTATGGGCTACAGAGTGAGTTCAAAGCCACTTTGGACAAGCTCATGAGAGGAGATGTGTGTTTTTAAAATGCTACAGTAAGAGCTGGTGAGATGGCCTCAGCAAGGAAAGGTACTTGCTTGCCAAGCTCAGTGACCAGAGTTTAATCCTTGGACCCCACATCACATGGTGGACAGAAGAGCCAGCTGTCCTAAGTGGTTCTCTGACATGACAAATGCAGTTCAGGGGTGTACCCCTCAAAAATACACACTGAATGCATGAGTAGACAGTAACAAATAAAAGGGGGTAGTAATATAACGTAGTAATGTGCTTGCCTAGCATATGAGAAACCCTAACCCATCCCACAGAAGGAAAGAGCATTGTTGCATCTGTGTAATTGCCACTATATTTGCTGTTTCAGACCTTTAGTGAGGTATGGTCTTTATTTGCACCAATATTGACTTTAAAAGTGAAAATTACTAATTGTGAAGAGAAAATGGATTTAGCTGTGTCCTTTTTCTGTTTTCATGTCGCTATTTGTTTTTTCTAATAATTTGTAAAATTATAATTATCTTAATAAACACTATGGTTTTGTTTTCATAGGCTTTCATTGTTATTCAGGCCTGTTTCAAATTCCTGGGCTCAACTAGTCCTCCTGAGCACTTGGGATTACAGGCGAGAGTTGTATTATATGCAACTTTTAAAGCAACTTAATTGGTATTTGGTGACATAAAAACTTGATACCTCTTTATTCATGATAGAGGTGAAGAATTTATTGTAAATATAACCATAATTTTAAAGGATGTCTGAACTGTTGTTGGGCACAACTGCAGTAGAGCTGTTCTGTCTCCTTCCTTTTGTGAGGGGGCAGAGGCATAAGTAGGGCCTTGCACTAATGAAGTAAGCAGGTGGTTCCCAGCAGAGCTAGGCCTCTGCCCCTAGCTTACCTCATTTCCCTTTATGCTGTCTTTCAGGTGCCAAAAAGGTAATTTTCTCTGCTTAACTATGTCATGGCTTGAGGTGTATTGACAACCTTGGTGTTCATTTTGCAG
Seq C2 exon
TGCTCAGTTTGCCGGGCTGCTTTGTGAAGAAGAAGGGAATGGCGCAGACAATGTTCAATACTGTGGCTACTGTAAATACCACTTTAGTAAGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026743:ENSMUST00000114680:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF138321=zf-HC5HC2H_2=FE(28.8=100)
A:
NA
C2:
PF138321=zf-HC5HC2H_2=PD(22.9=84.4),PF105004=SR-25=PU(29.5=71.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTGCTATATATGTGATGAACAAGG
R:
CAGCTTACTAAAGTGGTATTTACAGT
Band lengths:
198-1568
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types