GgaEX6015397 @ galGal3
Exon Skipping
Gene
ENSGALG00000002546 | Q90689_CHICK
Description
NA
Coordinates
chr17:8149719-8172866:+
Coord C1 exon
chr17:8149719-8149881
Coord A exon
chr17:8170712-8170843
Coord C2 exon
chr17:8172720-8172866
Length
132 bp
Sequences
Splice sites
3' ss Seq
TTTGGTTTCCCTCCCCGCAGGGC
3' ss Score
12.31
5' ss Seq
TACGTGAGT
5' ss Score
7.77
Exon sequences
Seq C1 exon
GTGGCACAGGGTCGCCATCAGCGTGCAGAAGAAAAACGTCACCTTGATTTTGGACTGTAAAAAGAAAATAACCAAGTTCTTGGATCGAAGCGACCATCCCATCATTGACGTCAATGGCATCATCGTATTTGGAACGAGGATATTAGATGAGGAAGTCTTCGAG
Seq A exon
GGCGACATCCAGCAGCTGCTGATCGTGGCCGACCCCCGGGCAGCCCACGACTACTGTGAGCACTACAGCCCCGACTGTGACACCGCCGTCCCCGATGCTCCACAATCCCAGGACCCCAACCAGGATGAATAC
Seq C2 exon
TATACCGATGGGGAGGGAGAAGGGGACACCTACTACTATGAGTACCCCTACTATGAAGACGTTGATGAAGCTGTAAAGCCTGAAGCACCCACCACCAAACCTGCACCCCCAGGAGTGGCTGCTGGAGAGAGACCCGAAACCAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000002546-'3-6,'3-5,4-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.532 C2=0.831
Domain overlap (PFAM):
C1:
PF0221019=Laminin_G_2=FE(56.2=100)
A:
PF0221019=Laminin_G_2=PD(9.4=20.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Human
(hg38)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCATCAGCGTGCAGAAGAAA
R:
GTGGGTGCTTCAGGCTTTACA
Band lengths:
242-374
Functional annotations
There are 1 annotated functions for this event
PMID: 12145749
[Not physiological]. Pro-alpha1(V) chains with abnormal N-propeptides were secreted and were incorporated into extracellular matrix, and the mutation resulted in dramatic alterations in collagen fibril structure. Note: also refers to a cryptic splice site.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]