GgaEX6039829 @ galGal3
Exon Skipping
Gene
ENSGALG00000003135 | Q90717_CHICK
Description
NA
Coordinates
chr6:10105883-10116681:+
Coord C1 exon
chr6:10105883-10106006
Coord A exon
chr6:10108886-10108988
Coord C2 exon
chr6:10116575-10116681
Length
103 bp
Sequences
Splice sites
3' ss Seq
ATAAATGGTAAATACAACAGCCT
3' ss Score
-1.29
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
GTGAGGATGCAATGACAGGTGACACGGACAAGTATCTCGGACCCCAGGATCTAAAAGAGTTGGGCGATGATTCTTTGCCTGCTGAAGGCTACATGGGCTTTAGCCTGGGAGCCCGCTCTGCCAG
Seq A exon
CCTCCGCTCCTTCAGTTCGGATAGGTCCTACACTCTGAACAGAAGTTCTTATGCCCGAGACAGCATGATGATTGAAGAGCTGCTGGTACCAGCGAAGGATCAG
Seq C2 exon
CACCTGACGTTTCAGAGGGAGTTTGATTCTGATTCTCTCAGACACTACAGCTGGGCTGCAGACACCTTGGACAATGTTAACCTTGTTTCAAGTCCCATCCATTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003135-'30-31,'30-29,32-31=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.429 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0079115=ZU5=PU(1.0=2.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGATGCAATGACAGGTGACAC
R:
CCAGAATGGATGGGACTTGAAACA
Band lengths:
228-331
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]