MmuEX0004926 @ mm10
Exon Skipping
Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69927695-69951058:+
Coord C1 exon
chr10:69927695-69927818
Coord A exon
chr10:69932394-69932496
Coord C2 exon
chr10:69950952-69951058
Length
103 bp
Sequences
Splice sites
3' ss Seq
GGTGACTGTAAATACAACAGCCT
3' ss Score
-0.19
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
GTGAAGATGCCATCACAGGGGACACTGACAAGTATCTCGGGCCACAGGACCTTAAGGAGCTAGGTGATGACTCCCTGCCAGCAGAAGGTTACGTAGGCTTCAGTCTTGGAGCCCGTTCTGCCAG
Seq A exon
CCTCCGCTCCTTCAGTTCGGATAGGTCCTACACCTTGAACAGAAGCTCCTACGCAAGGGACAGCATGATGATAGAGGAACTTCTGGTACCATCCAAAGAGCAG
Seq C2 exon
CACCTGACGTTCACGAGGGAGTTTGATTCTGACTCCCTCAGACACTACAGTTGGGCAGCGGACACGTTAGATAATGTGAACCTGGTCTCAAGCCCGGTGCATTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601-'64-83,'64-81,66-83
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.381 A=0.004 C2=0.022
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0079115=ZU5=PU(1.0=2.8)
Other Inclusion Isoforms:
ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090089, ENSMUSP00000090090, ENSMUSP00000138095, ENSMUSP00000138123, ENSMUSP00000138285, ENSMUSP00000138326, ENSMUSP00000138337, ENSMUSP00000138347, ENSMUSP00000138348, ENSMUSP00000138375, ENSMUSP00000138413, ENSMUSP00000138481, ENSMUSP00000138586, ENSMUSP00000138623, ENSMUSP00000138671, ENSMUSP00000138686, ENSMUSP00000138770, ENSMUSP00000151906
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAAGATGCCATCACAGGGG
R:
GAATGCACCGGGCTTGAGAC
Band lengths:
228-331
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
This event
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types