RnoEX0009395 @ rn6
Exon Skipping
Gene
ENSRNOG00000053288 | Ank3
Description
ankyrin 3 [Source:RGD Symbol;Acc:620157]
Coordinates
chr20:20380700-20403795:+
Coord C1 exon
chr20:20380700-20380823
Coord A exon
chr20:20385488-20385590
Coord C2 exon
chr20:20403689-20403795
Length
103 bp
Sequences
Splice sites
3' ss Seq
CTGTAAATATTNNACAACAGCCT
3' ss Score
0
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
GTGAAGATGCCATCACAGGGGACACTGACAAGTATCTCGGGCCACAGGACCTCAAGGAGCTGGGCGATGACTCCCTGCCTGCCGAGGGCTATGTGGGCTTCAGTCTCGGAGCCCGTTCTGCCAG
Seq A exon
CCTTCGCTCCTTCAGTTCGGATAGGTCCTACACCCTGAACAGAAGCTCCTATGCGCGGGACAGCATGATGATCGAGGAGCTTCTGGTGCCATCCAAAGAGCAG
Seq C2 exon
CACCTTCCATTCACGAGGGAGTTTGACTCCGACTCCCTCAGACACTACAGTTGGGCAGCAGACACACTGGACAATGTGAACCTGGTCTCCAGCCCTGTGCATTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000053288_MULTIEX4-1/3=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.470 A=0.000 C2=0.042
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0079115=ZU5=PU(1.0=2.8)
Main Skipping Isoform:
ENSRNOT00000079630fB1069
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAAGATGCCATCACAGGGG
R:
GAATGCACAGGGCTGGAGAC
Band lengths:
228-331
Functional annotations
There are 1 annotated functions for this event
PMID: 26024478
The paper describes and annotates all exons to an extreme detail. Wild-type isoform, but not the variants (either skipping 31 or 28-31), bind beta-spectrin. Exon 28 (MmuEX0004926), exon 29 (MmuEX6048924), exon 31 (MmuEX6048923)
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]