HsaEX0002213 @ hg19
Exon Skipping
Gene
ENSG00000121989 | ACVR2A
Description
activin A receptor, type IIA [Source:HGNC Symbol;Acc:173]
Coordinates
chr2:148657313-148672903:+
Coord C1 exon
chr2:148657313-148657467
Coord A exon
chr2:148669106-148669129
Coord C2 exon
chr2:148672760-148672903
Length
24 bp
Sequences
Splice sites
3' ss Seq
CTGTGTTTTTTCTTCACAAGCAC
3' ss Score
4.99
5' ss Seq
GAGGTAAGA
5' ss Score
10.06
Exon sequences
Seq C1 exon
CCACTTCAAATCCAGTTACACCTAAGCCACCCTATTACAACATCCTGCTCTATTCCTTGGTGCCACTTATGTTAATTGCGGGGATTGTCATTTGTGCATTTTGGGTGTACAGGCATCACAAGATGGCCTACCCTCCTGTACTTGTTCCAACTCAA
Seq A exon
CACGCCTTTCATATAATGATAGAG
Seq C2 exon
GACCCAGGACCACCCCCACCTTCTCCATTACTAGGTTTGAAACCACTGCAGTTATTAGAAGTGAAAGCAAGGGGAAGATTTGGTTGTGTCTGGAAAGCCCAGTTGCTTAACGAATATGTGGCTGTCAAAATATTTCCAATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121989_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.077 A=0.000 C2=0.014
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0006920=Pkinase=PU(11.1=66.7)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGGGGATTGTCATTTGTGCA
R:
TAATGGAGAAGGTGGGGGTGG
Band lengths:
108-132
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)