HsaEX0002423 @ hg19
Exon Skipping
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136291319-136295301:+
Coord C1 exon
chr9:136291319-136291465
Coord A exon
chr9:136293754-136293891
Coord C2 exon
chr9:136294820-136295301
Length
138 bp
Sequences
Splice sites
3' ss Seq
ACTCCCCGCCCCCCGACCAGCTT
3' ss Score
5.13
5' ss Seq
CAGGTAGCG
5' ss Score
7.38
Exon sequences
Seq C1 exon
GTTTGACCTGGAGTTGCCTGATGGTAACCGGCAGGTGCGGGGCGTCACCCAGCTGGGCGGTGCCTGCTCCCCAACCTGGAGCTGCCTCATTACCGAGGACACTGGCTTCGACCTGGGAGTCACCATTGCCCATGAGATTGGGCACAG
Seq A exon
CTTCGGCCTGGAGCACGACGGCGCGCCCGGCAGCGGCTGCGGCCCCAGCGGACACGTGATGGCTTCGGACGGCGCCGCGCCCCGCGCCGGCCTCGCCTGGTCCCCCTGCAGCCGCCGGCAGCTGCTGAGCCTGCTCAG
Seq C2 exon
ACCCGTCCCTCCGTCGCCGCTCCCTCTGCTGGCCACCCACCTCTGCGCCGGCAGGAGCCTTAGTCTTGGTCCCAGCCAAGAGCCGGCTCCTGGTGGGGGGCGCGGGCCGAGAACTCCTGTTCCCACTCACAAAAGGCCACGCTTCCAAACGCTTCCATCCTCGTGCCCACTCCTCCGTCCCGCCTCCTCCCGGTGTACACCCCGGGACTGAGCCGGGCCTGAGCCGGGCCTTGTCGCAGCGCAGGACGGGCGCGCTGCGTGTGGGACCCGCCGCGGCCTCAACCCGGGTCCGCGGGGCACCCGCCGGATGCGCAGCCTGGCCTCTACTACAGCGCCAACGAGCAGTGCCGCGTGGCCTTCGGCCCCAAGGCTGTCGCCTGCACCTTCGCCAGGGAGCACCTGGTGAGTCTGCCGGCGGTGGCCTGGGATTGGCTGTGAGGTCCCTCCGCATCACCCAGCTCACGTCCCCCAAAACGTGCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-'7-9,'7-8,8-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.037 A=0.221 C2=0.614
Domain overlap (PFAM):
C1:
PF135821=Reprolysin_3=FE(40.5=100)
A:
PF0142114=Reprolysin=FE(22.3=100)
C2:
PF0142114=Reprolysin=PD(2.5=7.0)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGTCACCATTGCCCATGAG
R:
CTCAGTCCCGGGGTGTACAC
Band lengths:
244-382
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)