HsaEX0004122 @ hg38
Exon Skipping
Gene
ENSG00000145362 | ANK2
Description
ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]
Coordinates
chr4:113255735-113258411:+
Coord C1 exon
chr4:113255735-113255932
Coord A exon
chr4:113258050-113258148
Coord C2 exon
chr4:113258313-113258411
Length
99 bp
Sequences
Splice sites
3' ss Seq
CTTGATTGTCTTTTGCACAGAAT
3' ss Score
5.48
5' ss Seq
GAGGTAGAA
5' ss Score
4.54
Exon sequences
Seq C1 exon
AATGGGCTGTCTCCACTACACATGGCTGCCCAGGGAGACCACGTGGAATGTGTGAAGCACCTGTTACAGCACAAGGCACCTGTTGATGATGTCACCCTAGACTACCTGACAGCCCTCCACGTTGCTGCGCACTGTGGCCACTACCGTGTAACCAAACTCCTTTTAGACAAGAGAGCCAATCCGAACGCCAGAGCCCTG
Seq A exon
AATGGTTTTACTCCACTGCACATTGCCTGCAAGAAAAACCGCATCAAAGTCATGGAACTGCTGGTGAAATATGGGGCTTCAATCCAAGCTATAACAGAG
Seq C2 exon
TCTGGCCTCACACCAATACATGTGGCTGCCTTCATGGGCCACTTGAACATTGTCCTCCTTCTGCTGCAGAACGGAGCCTCTCCAGATGTCACTAACATT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145362-'35-43,'35-41,36-43
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(33.3=47.0),PF136371=Ank_4=PU(57.4=47.0)
A:
PF127962=Ank_2=PD(33.3=93.9),PF127962=Ank_2=PU(10.8=24.2)
C2:
PF127962=Ank_2=FE(45.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCACCTGTTACAGCACAAGG
R:
AGGCAGCCACATGTATTGGTG
Band lengths:
174-273
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development