HsaEX0006290 @ hg38
Exon Skipping
Gene
ENSG00000126522 | ASL
Description
argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]
Coordinates
chr7:66076039-66086662:+
Coord C1 exon
chr7:66076039-66076093
Coord A exon
chr7:66083077-66083174
Coord C2 exon
chr7:66086585-66086662
Length
98 bp
Sequences
Splice sites
3' ss Seq
ACCATCTCCTCCTTGCACAGGTG
3' ss Score
10.23
5' ss Seq
GGCGTGAGT
5' ss Score
7
Exon sequences
Seq C1 exon
ACCCGGAGGACCGAAGCTTCCGGACGACGAGGAACCGCCCAACATGGCCTCGGAG
Seq A exon
GTGGTCACAGACCTCAGGCTGTGGATGCGGCAGACCTGCTCCACGCTCTCGGGCCTCCTCTGGGAGCTCATTAGGACCATGGTGGATCGGGCAGAGGC
Seq C2 exon
GGAACGTGATGTTCTCTTCCCGGGGTACACCCATTTGCAGAGGGCCCAGCCCATCCGCTGGAGCCACTGGATTCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126522_MULTIEX2-4/8=C1-5
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0020615=Lyase_1=FE(10.8=100)
C2:
PF0020615=Lyase_1=FE(15.8=100),PF0020615=Lyase_1=PU(1.9=7.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGACCGAAGCTTCCGGA
R:
CTCAGAATCCAGTGGCTCCAG
Band lengths:
128-226
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development