HsaEX0006287 @ hg38
Exon Skipping
Gene
ENSG00000126522 | ASL
Description
argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]
Coordinates
chr7:66076039-66082451:+
Coord C1 exon
chr7:66076039-66076093
Coord A exon
chr7:66081803-66081997
Coord C2 exon
chr7:66082368-66082451
Length
195 bp
Sequences
Splice sites
3' ss Seq
GTTCTTGCTCTCCTGGCCAGAGT
3' ss Score
5.57
5' ss Seq
AAGGTACTT
5' ss Score
8.4
Exon sequences
Seq C1 exon
ACCCGGAGGACCGAAGCTTCCGGACGACGAGGAACCGCCCAACATGGCCTCGGAG
Seq A exon
AGTGGGAAGCTTTGGGGTGGCCGGTTTGTGGGTGCAGTGGACCCCATCATGGAGAAGTTCAACGCGTCCATTGCCTACGACCGGCACCTTTGGGAGGTGGATGTTCAAGGCAGCAAAGCCTACAGCAGGGGCCTGGAGAAGGCAGGGCTCCTCACCAAGGCCGAGATGGACCAGATACTCCATGGCCTAGACAAG
Seq C2 exon
GTGGCTGAGGAGTGGGCCCAGGGCACCTTCAAACTGAACTCCAATGATGAGGACATCCACACAGCCAATGAGCGCCGCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126522_MULTIEX2-1/8=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.056
Domain overlap (PFAM):
C1:
NO
A:
PF0020615=Lyase_1=PU(19.7=89.2)
C2:
PF0020615=Lyase_1=FE(11.2=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGACCGAAGCTTCCGGA
R:
CTTCAGGCGGCGCTCATTG
Band lengths:
134-329
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development