HsaEX0008410 @ hg38
Exon Skipping
Gene
ENSG00000204256 | BRD2
Description
bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103]
Coordinates
chr6:32974462-32975521:+
Coord C1 exon
chr6:32974462-32974765
Coord A exon
chr6:32975021-32975112
Coord C2 exon
chr6:32975384-32975521
Length
92 bp
Sequences
Splice sites
3' ss Seq
GCCCTGGCTCCATTTTACAGATT
3' ss Score
9.25
5' ss Seq
GAGGTAATG
5' ss Score
8.73
Exon sequences
Seq C1 exon
GCTCCCTGGGGAAGGGAATGCAGGGTTGCTGGGGCTGGGCCCAGAAGCAGCAGCACCAGGGAAGAGGATTCGAAAACCCTCTCTCTTGTATGAGGGCTTTGAGAGCCCCACAATGGCTTCGGTGCCTGCTTTGCAACTTACCCCTGCCAACCCACCACCCCCGGAGGTGTCCAATCCCAAAAAGCCAGGACGAGTTACCAACCAGCTGCAATACCTACACAAGGTAGTGATGAAGGCTCTGTGGAAACATCAGTTCGCATGGCCATTCCGGCAGCCTGTGGATGCTGTCAAACTGGGTCTACCG
Seq A exon
ATTCCCACCTCGGGTTGGGAGAGGACCACGGTGGCCAAAATTCTTAGCTTCTTCCTTTCCCTCATGCAGCCCATGGATAGCCAGCCCCAGAG
Seq C2 exon
GATTATCACAAAATTATAAAACAGCCTATGGACATGGGTACTATTAAGAGGAGACTTGAAAACAATTATTATTGGGCTGCTTCAGAGTGTATGCAAGATTTTAATACCATGTTCACCAACTGTTACATTTACAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204256_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.412 A=0.000 C2=0.003
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PU(31.8=26.5)
A:
NO
C2:
PF0043920=Bromodomain=FE(52.9=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCAAAAAGCCAGGACGAGTT
R:
AGTACCCATGTCCATAGGCTGT
Band lengths:
171-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development