HsaEX0014014 @ hg19
Exon Skipping
Gene
ENSG00000158402 | CDC25C
Description
cell division cycle 25 homolog C (S. pombe) [Source:HGNC Symbol;Acc:1727]
Coordinates
chr5:137625190-137627805:-
Coord C1 exon
chr5:137627659-137627805
Coord A exon
chr5:137626328-137626429
Coord C2 exon
chr5:137625190-137625252
Length
102 bp
Sequences
Splice sites
3' ss Seq
GGGAATCTTGTCATCTTCAGGGC
3' ss Score
7.7
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GTGAGCAGAAGTGGCCTATATCGCTCCCCGTCGATGCCAGAGAACTTGAACAGGCCAAGACTGAAGCAGGTGGAAAAATTCAAGGACAACACAATACCAGATAAAGTTAAAAAAAAGTATTTTTCTGGCCAAGGAAAGCTCAGGAAG
Seq A exon
GGCTTATGTTTAAAGAAGACAGTCTCTCTGTGTGACATTACTATCACTCAGATGCTGGAGGAAGATTCTAACCAGGGGCACCTGATTGGTGATTTTTCCAAG
Seq C2 exon
GTATGTGCGCTGCCAACCGTGTCAGGGAAACACCAAGATCTGAAGTATGTCAACCCAGAAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158402_MULTIEX1-1/2=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.523 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=PU(71.6=98.0)
A:
PF066178=M-inducer_phosp=PD(14.3=50.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAGCAGAAGTGGCCTATATCG
R:
TGTTTCTGGGTTGACATACTTCAGA
Band lengths:
210-312
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)