HsaEX0014148 @ hg19
Exon Skipping
Gene
ENSG00000039068 | CDH1
Description
cadherin 1, type 1, E-cadherin (epithelial) [Source:HGNC Symbol;Acc:1748]
Coordinates
chr16:68842596-68845762:+
Coord C1 exon
chr16:68842596-68842751
Coord A exon
chr16:68844100-68844244
Coord C2 exon
chr16:68845587-68845762
Length
145 bp
Sequences
Splice sites
3' ss Seq
CCCTCACTTGGTTCTTTCAGCTC
3' ss Score
8.53
5' ss Seq
CAGGTATAT
5' ss Score
7.88
Exon sequences
Seq C1 exon
ATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTGGTGTCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACT
Seq A exon
CTCTTCTCTCACGCTGTGTCATCCAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCACCCAGGAGGTCTTTAAGGGGTCTGTCATGGAAGGTGCTCTTCCAG
Seq C2 exon
GAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATGTGAACACCTACAATGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACACAGGAGTCATCAGTGTGGTCACCACTGGGCTGGACCGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000039068-'7-7,'7-6,8-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.115 A=0.378 C2=0.267
Domain overlap (PFAM):
C1:
PF0002812=Cadherin=FE(53.7=100)
A:
PF0002812=Cadherin=PD(24.2=46.9),PF0002812=Cadherin=PU(11.0=22.4)
C2:
PF0002812=Cadherin=FE(58.0=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCCCCTGTTGGTGTCTTTA
R:
GGTGACCACACTGATGACTCC
Band lengths:
250-395
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)