HsaEX0017146 @ hg38
Exon Skipping
Gene
ENSG00000148204 | CRB2
Description
crumbs 2, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:18688]
Coordinates
chr9:123367172-123370980:+
Coord C1 exon
chr9:123367172-123367357
Coord A exon
chr9:123367573-123367686
Coord C2 exon
chr9:123370108-123370980
Length
114 bp
Sequences
Splice sites
3' ss Seq
CACAGCTGGGCCTCTTACAGGAG
3' ss Score
5.02
5' ss Seq
CAGGTGTCT
5' ss Score
2.68
Exon sequences
Seq C1 exon
GCTACAGCGGCGAGCTGTGCGAGGTGGACGAGGACGAGTGTGCATCGAGCCCCTGCCAGCATGGGGGCCGATGCCTGCAGCGCTCTGACCCGGCCCTCTACGGGGGTGTCCAGGCCGCCTTCCCTGGCGCCTTCAGCTTCCGCCATGCTGCGGGTTTCCTGTGCCACTGCCCTCCTGGCTTTGAGG
Seq A exon
GAGCCGACTGCGGTGTGGAGGTGGACGAGTGTGCCTCACGGCCATGCCTCAACGGAGGCCACTGCCAGGACCTGCCCAATGGCTTCCAGTGTCACTGCCCAGATGGCTACGCAG
Seq C2 exon
GGCCGACATGTGAGGAAGATGTGGATGAATGCCTGTCGGATCCCTGCCTGCACGGCGGAACCTGCAGTGACACTGTGGCAGGCTATATCTGCAGGTGCCCAGAGACCTGGGGTGGGCGCGACTGTTCTGTGCAGCTCACTGGCTGCCAGGGCCACACCTGCCCGCTGGCTGCCACCTGCATCCCTATCTTCGAGTCTGGGGTCCACAGTTACGTCTGCCACTGCCCACCTGGTACCCATGGACCGTTCTGTGGCCAGAATACCACCTTCTCTGTGATGGCTGGGAGCCCCATTCAGGCATCAGTGCCAGCTGGTGGCCCCCTGGGTCTGGCACTGAGGTTTCGCACCACACTGCCCGCTGGGACCTTGGCCACTCGCAATGACACCAAGGAAAGCTTGGAGCTGGCATTGGTGGCAGCCACACTTCAGGCCACACTCTGGAGCTACAGCACCACTGTGCTTGTCCTGAGACTGCCGGACCTGGCCCTAAACGATGGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148204_MULTIEX1-4/4=3-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(16.1=7.9),PF126612=hEGF=PU(69.2=14.3)
A:
PF126612=hEGF=PD(23.1=7.7),PF0000822=EGF=PU(90.3=71.8)
C2:
PF0000822=EGF=PD(6.5=0.7),PF0000822=EGF=WD(100=10.6),PF0221019=Laminin_G_2=WD(100=42.5),PF0000822=EGF=WD(100=10.6)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGAGGACGAGTGTGCATC
R:
ATAGCCTGCCACAGTGTCACT
Band lengths:
246-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development