HsaEX0018272 @ hg38
Exon Skipping
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]
Coordinates
chr19:41009219-41012485:+
Coord C1 exon
chr19:41009219-41009395
Coord A exon
chr19:41009994-41010135
Coord C2 exon
chr19:41012298-41012485
Length
142 bp
Sequences
Splice sites
3' ss Seq
CTTCCCTACTGTGGACGCAGGAG
3' ss Score
5.73
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
CTGTTTGAGCTCTTCTCTGGCTTCTTGAAATACTTTCCTGGGGCACACAGGCAAGTTTACAAAAACCTGCAGGAAATCAATGCTTACATTGGCCACAGTGTGGAGAAGCACCGTGAAACCCTGGACCCCAGCGCCCCCAAGGACCTCATCGACACCTACCTGCTCCACATGGAAAAA
Seq A exon
GAGAAATCCAACGCACACAGTGAATTCAGCCACCAGAACCTCAACCTCAACACGCTCTCGCTCTTCTTTGCTGGCACTGAGACCACCAGCACCACTCTCCGCTACGGCTTCCTGCTCATGCTCAAATACCCTCATGTTGCAG
Seq C2 exon
AGAGAGTCTACAGGGAGATTGAACAGGTGATTGGCCCACATCGCCCTCCAGAGCTTCATGACCGAGCCAAAATGCCATACACAGAGGCAGTCATCTATGAGATTCAGAGATTTTCCGACCTTCTCCCCATGGGTGTGCCCCACATTGTCACCCAACACACCAGCTTCCGAGGGTACATCATCCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408-'17-15,'17-14,19-15
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.111
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(12.7=100)
A:
PF0006717=p450=FE(10.3=100)
C2:
PF0006717=p450=PD(1.1=1.6),PF0006717=p450=FE(36.7=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGAGAAGCACCGTGAAAC
R:
GCTGGTGTGTTGGGTGACAAT
Band lengths:
243-385
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development