HsaEX0018276 @ hg38
Exon Skipping
Gene
ENSG00000100197 | CYP2D6
Description
cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625]
Coordinates
chr22:42127447-42128350:-
Coord C1 exon
chr22:42128174-42128350
Coord A exon
chr22:42127842-42127983
Coord C2 exon
chr22:42127447-42127634
Length
142 bp
Sequences
Splice sites
3' ss Seq
ATGCTCTCGGCCCTGCTCAGGCC
3' ss Score
4.85
5' ss Seq
AGCGTGAGC
5' ss Score
4.09
Exon sequences
Seq C1 exon
GTGCTGAATGCTGTCCCCGTCCTCCTGCATATCCCAGCGCTGGCTGGCAAGGTCCTACGCTTCCAAAAGGCTTTCCTGACCCAGCTGGATGAGCTGCTAACTGAGCACAGGATGACCTGGGACCCAGCCCAGCCCCCCCGAGACCTGACTGAGGCCTTCCTGGCAGAGATGGAGAAG
Seq A exon
GCCAAGGGGAACCCTGAGAGCAGCTTCAATGATGAGAACCTGCGCATAGTGGTGGCTGACCTGTTCTCTGCCGGGATGGTGACCACCTCGACCACGCTGGCCTGGGGCCTCCTGCTCATGATCCTACATCCGGATGTGCAGC
Seq C2 exon
GCCGTGTCCAACAGGAGATCGACGACGTGATAGGGCAGGTGCGGCGACCAGAGATGGGTGACCAGGCTCACATGCCCTACACCACTGCCGTGATTCATGAGGTGCAGCGCTTTGGGGACATCGTCCCCCTGGGTGTGACCCATATGACATCCCGTGACATCGAAGTACAGGGCTTCCGCATCCCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100197-'6-13,'6-9,7-13
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.149 A=0.113 C2=0.130
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(17.6=100)
A:
PF0006717=p450=FE(14.2=100)
C2:
PF0006717=p450=FE(18.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAGGTCCTACGCTTCCAAA
R:
AAAGCGCTGCACCTCATGAAT
Band lengths:
244-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development