HsaEX0020187 @ hg38
Exon Skipping
Gene
ENSG00000158486 | DNAH3
Description
dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr16:20936649-20944663:-
Coord C1 exon
chr16:20944496-20944663
Coord A exon
chr16:20941401-20941543
Coord C2 exon
chr16:20936649-20936853
Length
143 bp
Sequences
Splice sites
3' ss Seq
TCTTCTGCCTGCATTTTAAGGAA
3' ss Score
8.99
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
TCCTATATCGACTATCTCAGGAATCTCCCCATCACAGCCCACCCAGAAGTGTTCGGCCTCCATGAGAACGCAGACATCACCAAAGACAACCAGGAAACCAACCAGCTGTTTGAGGGGGTCCTGCTGACCCTCCCTAGACAGTCAGGAGGAAGTGGCAAGTCCCCTCAG
Seq A exon
GAAGTGGTTGAGGAGTTGGCACAAGACATTCTCTCCAAGCTTCCCAGAGACTTTGACCTGGAAGAGGTCATGAAGTTGTACCCCGTGGTCTATGAAGAATCCATGAATACCGTCCTAAGGCAGGAGCTCATCAGATTCAACAG
Seq C2 exon
GCTGACCAAAGTGGTTCGGAGGAGCCTCATCAATCTTGGCCGAGCCATCAAAGGACAGGTCCTGATGTCCTCGGAGCTAGAGGAAGTCTTTAACAGCATGCTTGTGGGTAAAGTGCCAGCCATGTGGGCAGCCAAGTCTTACCCATCACTGAAGCCTCTGGGGGGCTACGTGGCTGACCTGCTGGCCCGCCTGACCTTCTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-'93-99,'93-98,94-99
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.161 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(14.1=100)
A:
PF0302810=Dynein_heavy=FE(12.1=100)
C2:
PF0302810=Dynein_heavy=FE(17.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGTGTTCGGCCTCCATGAG
R:
CTGGCACTTTACCCACAAGCA
Band lengths:
242-385
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development