HsaEX0020199 @ hg38
Exon Skipping
Gene
ENSG00000115423 | DNAH6
Description
dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]
Coordinates
chr2:84733444-84762945:+
Coord C1 exon
chr2:84733444-84733579
Coord A exon
chr2:84745080-84745249
Coord C2 exon
chr2:84762755-84762945
Length
170 bp
Sequences
Splice sites
3' ss Seq
TTTTTAAATTGTATTTCCAGGAT
3' ss Score
8.86
5' ss Seq
AAGGTAGGG
5' ss Score
8.76
Exon sequences
Seq C1 exon
GAACGCCCACCTAAGCCTGAAGCTCCCTGGCTACCTACTGCTACATGGTTCGCATGCTGTGACTTGGAAGAATCATTTCCAGTTTTTCACGGACTTACCCAAAATATATTGTCACATCCTATTTCCATACGCTTAG
Seq A exon
GATCTTTTGAGACTTATATTAACCCACAGAAATGGGAAGGCTATTCTAAAATGAAACACGAAGATAAACACATGAGACAGGAAAAGGAGGCAGCACACCAAGATCCATGGAGTGCAGGATTGAGTTCTTTCCATAAGCTAATTCTTATTAAATGTTGTAAAGAAGAAAAG
Seq C2 exon
GTGGTTTTTGCTCTTACAGACTTTGTGATAGAAAATCTTGGAAAACAGTTTATAGAGACACCACCTGTGGACCTGCCTACCCTGTATCAAGACATGTCATGCAACACTCCCCTGGTATTCATCCTAAGCACAGGCTCAGATCCCATGGGTGCATTTCAGAGGTTTGCCAGGGAAAGTGGATATTCAGAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115423-'84-87,'84-85,85-87
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=0.246 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(10.5=100)
A:
PF0302810=Dynein_heavy=FE(13.1=100)
C2:
PF0302810=Dynein_heavy=FE(14.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGTTCGCATGCTGTGACTT
R:
CCTCTGAAATGCACCCATGGG
Band lengths:
254-424
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development