HsaEX0020453 @ hg19
Exon Skipping
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10912964-10916643:+
Coord C1 exon
chr19:10912964-10913034
Coord A exon
chr19:10914315-10914344
Coord C2 exon
chr19:10916592-10916643
Length
30 bp
Sequences
Splice sites
3' ss Seq
GGCCTTCCCACTTACCCCAGCTG
3' ss Score
5.66
5' ss Seq
CTGGTGGGT
5' ss Score
6.29
Exon sequences
Seq C1 exon
ATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAA
Seq A exon
CTGTTACTATACTGAGCAGCTGGTGACCTG
Seq C2 exon
TGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-'16-16,'16-15,17-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.071
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(19.3=100)
A:
PF0103115=Dynamin_M=FE(18.8=100)
C2:
PF0103115=Dynamin_M=PD(10.1=66.7)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGCTGATCGACATTGAGCA
R:
TGGGGATGGCTCTCTTCTTGT
Band lengths:
113-143
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)