HsaEX0020681 @ hg19
Exon Skipping
Gene
ENSG00000115325 | DOK1
Description
docking protein 1, 62kDa (downstream of tyrosine kinase 1) [Source:HGNC Symbol;Acc:2990]
Coordinates
chr2:74782702-74784681:+
Coord C1 exon
chr2:74782702-74782795
Coord A exon
chr2:74783021-74783205
Coord C2 exon
chr2:74783435-74784681
Length
185 bp
Sequences
Splice sites
3' ss Seq
TAATCGTGTATGCCTTCCAGGAT
3' ss Score
6.83
5' ss Seq
AAGGTGCAG
5' ss Score
3.97
Exon sequences
Seq C1 exon
AAAGGCAGCTGGACTCTGGCGCCTACCGATAACCCACCTAAGCTTTCTGCCCTGGAGATGCTGGAGAACTCCTTGTACAGCCCTACCTGGGAAG
Seq A exon
GATCCCAATTCTGGGTAACGGTGCAGAGGACTGAGGCCGCCGAGCGCTGTGGCCTGCATGGCTCCTACGTGCTGAGGGTGGAGGCTGAAAGGCTGACTCTCCTGACCGTGGGGGCCCAGAGTCAGATACTGGAGCCACTCCTGTCCTGGCCCTACACTCTGTTGCGTCGCTATGGCCGGGACAAG
Seq C2 exon
GTCATGTTCTCTTTCGAGGCCGGCCGCCGCTGCCCCTCAGGCCCTGGAACCTTCACCTTCCAGACGGCACAGGGAAATGACATCTTCCAGGCAGTTGAGACTGCCATCCACCGGCAGAAGGCCCAGGGAAAGGCCGGACAGGGGCACGATGTTCTCAGAGCTGACTCCCATGAAGGGGAGGTGGCAGAGGGGAAGTTGCCTTCCCCACCTGGCCCCCAAGAGCTCCTCGACAGTCCCCCAGCCCTGTATGCTGAGCCCTTAGACTCCCTGCGCATTGCTCCATGCCCTTCCCAGGACTCCCTATACTCAGACCCCTTGGACAGCACGTCTGCTCAGGCAGGAGAGGGAGTACAACGGAAGAAACCTCTCTATTGGGACTTGTATGAGCATGCGCAGCAGCAGTTGCTGAAGGCCAAGCTGACAGACCCCAAAGAGGATCCCATCTATGATGAACCTGAGGGCCTGGCCCCAGTCCCTCCCCAGGGCCTTTATGATCTGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325_MULTIEX1-5/5=4-C2
Average complexity
S
Mappability confidence:
86%=86=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.078 A=0.010 C2=0.687
Domain overlap (PFAM):
C1:
PF0217412=IRS=PU(1.0=3.1)
A:
PF0217412=IRS=FE(58.7=100)
C2:
PF0217412=IRS=PD(38.5=14.9)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCCTACCGATAACCCACCTA
R:
TGGGAGTCAGCTCTGAGAACA
Band lengths:
245-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)