HsaEX0020681 @ hg38
Exon Skipping
Gene
ENSG00000115325 | DOK1
Description
docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]
Coordinates
chr2:74555575-74557536:+
Coord C1 exon
chr2:74555575-74555668
Coord A exon
chr2:74555894-74556078
Coord C2 exon
chr2:74556308-74557536
Length
185 bp
Sequences
Splice sites
3' ss Seq
TAATCGTGTATGCCTTCCAGGAT
3' ss Score
6.83
5' ss Seq
AAGGTGCAG
5' ss Score
3.97
Exon sequences
Seq C1 exon
AAAGGCAGCTGGACTCTGGCGCCTACCGATAACCCACCTAAGCTTTCTGCCCTGGAGATGCTGGAGAACTCCTTGTACAGCCCTACCTGGGAAG
Seq A exon
GATCCCAATTCTGGGTAACGGTGCAGAGGACTGAGGCCGCCGAGCGCTGTGGCCTGCATGGCTCCTACGTGCTGAGGGTGGAGGCTGAAAGGCTGACTCTCCTGACCGTGGGGGCCCAGAGTCAGATACTGGAGCCACTCCTGTCCTGGCCCTACACTCTGTTGCGTCGCTATGGCCGGGACAAG
Seq C2 exon
GTCATGTTCTCTTTCGAGGCCGGCCGCCGCTGCCCCTCAGGCCCTGGAACCTTCACCTTCCAGACGGCACAGGGAAATGACATCTTCCAGGCAGTTGAGACTGCCATCCACCGGCAGAAGGCCCAGGGAAAGGCCGGACAGGGGCACGATGTTCTCAGAGCTGACTCCCATGAAGGGGAGGTGGCAGAGGGGAAGTTGCCTTCCCCACCTGGCCCCCAAGAGCTCCTCGACAGTCCCCCAGCCCTGTATGCTGAGCCCTTAGACTCCCTGCGCATTGCTCCATGCCCTTCCCAGGACTCCCTATACTCAGACCCCTTGGACAGCACGTCTGCTCAGGCAGGAGAGGGAGTACAACGGAAGAAACCTCTCTATTGGGACTTGTATGAGCATGCGCAGCAGCAGTTGCTGAAGGCCAAGCTGACAGACCCCAAAGAGGATCCCATCTATGATGAACCTGAGGGCCTGGCCCCAGTCCCTCCCCAGGGCCTTTATGATCTGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325-'13-19,'13-18,18-19
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.091 A=0.015 C2=0.685
Domain overlap (PFAM):
C1:
PF0217412=IRS=PU(1.0=3.1)
A:
PF0217412=IRS=FE(58.7=100)
C2:
PF0217412=IRS=PD(38.5=14.9)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCCTACCGATAACCCACCTA
R:
TGGGAGTCAGCTCTGAGAACA
Band lengths:
245-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development