HsaEX0020680 @ hg38
Exon Skipping
Gene
ENSG00000115325 | DOK1
Description
docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]
Coordinates
chr2:74555154-74557554:+
Coord C1 exon
chr2:74555154-74555453
Coord A exon
chr2:74555575-74555668
Coord C2 exon
chr2:74556308-74557554
Length
94 bp
Sequences
Splice sites
3' ss Seq
CTCGATGCTCTCTACTACAGAAA
3' ss Score
6.94
5' ss Seq
AAGGTAGAC
5' ss Score
7.07
Exon sequences
Seq C1 exon
AGGTGGAGGAAGACCTGGGCCGTGCTCTACCCGGCCAGTCCCCACGGCGTAGCGCGGCTCGAGTTCTTTGACCATAAGGGGTCGAGCTCTGGGGGTGGCCGAGGGAGCTCGCGCCGCCTGGACTGCAAAGTGATCCGTCTGGCTGAGTGTGTGAGTGTGGCCCCCGTCACCGTGGAGACCCCCCCTGAGCCCGGCGCCACTGCCTTCCGCCTGGACACTGCTCAGCGCTCGCACCTGCTGGCGGCCGACGCGCCGTCCAGTGCAGCCTGGGTGCAGACGCTGTGCCGAAACGCCTTTCCG
Seq A exon
AAAGGCAGCTGGACTCTGGCGCCTACCGATAACCCACCTAAGCTTTCTGCCCTGGAGATGCTGGAGAACTCCTTGTACAGCCCTACCTGGGAAG
Seq C2 exon
GTCATGTTCTCTTTCGAGGCCGGCCGCCGCTGCCCCTCAGGCCCTGGAACCTTCACCTTCCAGACGGCACAGGGAAATGACATCTTCCAGGCAGTTGAGACTGCCATCCACCGGCAGAAGGCCCAGGGAAAGGCCGGACAGGGGCACGATGTTCTCAGAGCTGACTCCCATGAAGGGGAGGTGGCAGAGGGGAAGTTGCCTTCCCCACCTGGCCCCCAAGAGCTCCTCGACAGTCCCCCAGCCCTGTATGCTGAGCCCTTAGACTCCCTGCGCATTGCTCCATGCCCTTCCCAGGACTCCCTATACTCAGACCCCTTGGACAGCACGTCTGCTCAGGCAGGAGAGGGAGTACAACGGAAGAAACCTCTCTATTGGGACTTGTATGAGCATGCGCAGCAGCAGTTGCTGAAGGCCAAGCTGACAGACCCCAAAGAGGATCCCATCTATGATGAACCTGAGGGCCTGGCCCCAGTCCCTCCCCAGGGCCTTTATGATCTGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325_MULTIEX1-4/5=3-C2
Average complexity
C2*
Mappability confidence:
86%=86=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.161 A=0.091 C2=0.685
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(84.3=97.0)
A:
PF0217412=IRS=PU(1.0=3.1)
C2:
PF0217412=IRS=PD(38.5=14.9)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGCCGAAACGCCTTTCC
R:
CAGCTCTGAGAACATCGTGCC
Band lengths:
183-277
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development